Preparation, bioactivity, degradability and primary cell responses to an ordered mesoporous magnesium-calcium silicate
文献类型：期刊论文
| 作者 | Lu, JX ; Wei, J ; Gan, Q ; Lu, X ; Hou, J ; Song, WH ; Yan, YG ; Ma, J ; Guo, H（郭瀚） ; Xiao, TQ(肖体乔） ; Liu, CS |
| 刊名 | MICROPOROUS AND MESOPOROUS MATERIALS
 |
| 出版日期 | 2012 |
| 卷号 | 163 |
| ISSN号 | 1387-1811 |
| 英文摘要 | An ordered mesoporous calcium-magnesium silicate (om-CMS) for bone repair was synthesized and characterized, and the in vitro bioactivity, degradability and primary cell responses to the om-CMS were investigated. The results showed that the om-CMS possessed a large surface area of 1017 m(2)/g and highly ordered hexagonal channel pores of around 7 nm. The om-CMS had good bioactivity, which could induce apatite formation on its surfaces after 5 d of soaking in simulated body fluid (SBF), and the om-CMS exhibited enhanced bioactive behavior, with even faster apatite formation than calcium-magnesium silicate (CMS). Furthermore, the om-CMS could be degradable in Tris-HCI solution with the weight loss ratio of 40 wt.% after immersion for 84 d. In cell cultural experiments, the results revealed that om-CMS could promote proliferation and differentiation of the MC3T3-E1 cells with time, and the cells with a normal morphology spread well on the om-CMS surface, which showed no negative effects of the substrate on cells. In conclusion, the results demonstrated that the degradable om-CMS with good bioactivity had the ability to support cell attachment, proliferation and differentiation, and exhibited good cytocompatibility. (c) 2012 Elsevier Inc. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000309625800028 |
| 公开日期 | 2013-12-05 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/13254]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 推荐引用方式 GB/T 7714 | Lu, JX,Wei, J,Gan, Q,et al. Preparation, bioactivity, degradability and primary cell responses to an ordered mesoporous magnesium-calcium silicate[J]. MICROPOROUS AND MESOPOROUS MATERIALS,2012,163. |
| APA | Lu, JX.,Wei, J.,Gan, Q.,Lu, X.,Hou, J.,...&Liu, CS.(2012).Preparation, bioactivity, degradability and primary cell responses to an ordered mesoporous magnesium-calcium silicate.MICROPOROUS AND MESOPOROUS MATERIALS,163. |
| MLA | Lu, JX,et al."Preparation, bioactivity, degradability and primary cell responses to an ordered mesoporous magnesium-calcium silicate".MICROPOROUS AND MESOPOROUS MATERIALS 163(2012). |
入库方式： OAI收割
来源：上海应用物理研究所
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