Magnetic molecularly imprinted polymer for the selective extraction of sildenafil, vardenafil and their analogs from herbal medicines
文献类型：期刊论文
| 作者 | Chen FF(陈方方)1,2,3; Jie XY(解笑瑜)1,2,3; Shi YP(师彦平)1,2 ; Shi YP(师彦平)
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| 刊名 | Talanta
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| 出版日期 | 2013 |
| 卷号 | 115页码:482-489 |
| 关键词 | Magnetic molecularly imprinted polymers Herbal medicines Phosphodiesterase type-5 inhibitors Sildenafil Solid phase extraction |
| ISSN号 | 0039-9140 |
| 通讯作者 | 师彦平 |
| 英文摘要 | The successfully developed magnetic molecularly imprinted polymers (MMIPs) toward six synthetic phosphodiesterase type-5 (PDE-5) inhibitors were described. Sildenafil was used as template for the preparation of MMIPs using superparamagnetic core–shell nanoparticle as supporter. The obtained MMIPs were characterized using transmission electron microscope, Fourier transform infrared, X-ray diffraction, and vibrating sample magnetometer. High performance liquid chromatography (HPLC) with diode array detector (DAD) was used for the analysis of target analytes. The application of MMIPs as selective sorbent in the cleanup of herbal medicine samples prior to HPLC offered simple sample preparation. The adsorption capacity and selectivity of prepared MMIPs and magnetic non-molecularly imprinted polymers were investigated. The binding isotherms were obtained for sildenafil and fitted by Freundlich isotherm model. Structurally similar compound of sildenafil and a reference compound protocatechuic acid were used for investing the selective recognition of MMIPs. |
| 学科主题 | 分析化学与药物化学 |
| 收录类别 | SCI |
| 资助信息 | the National Natural Science Foundation of China (Nos. 21075127;20875095) |
| 语种 | 英语 |
| WOS记录号 | WOS:000328095600069 |
| 公开日期 | 2013-12-11 |
| 源URL | [http://210.77.64.217/handle/362003/4635]  |
| 专题 | 兰州化学物理研究所_中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| 通讯作者 | Shi YP(师彦平) |
| 作者单位 | 1.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem Northwest Plant Resources, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Grad Univ, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen FF,Jie XY,Shi YP,et al. Magnetic molecularly imprinted polymer for the selective extraction of sildenafil, vardenafil and their analogs from herbal medicines[J]. Talanta,2013,115:482-489. |
| APA | Chen FF,Jie XY,Shi YP,&师彦平.(2013).Magnetic molecularly imprinted polymer for the selective extraction of sildenafil, vardenafil and their analogs from herbal medicines.Talanta,115,482-489. |
| MLA | Chen FF,et al."Magnetic molecularly imprinted polymer for the selective extraction of sildenafil, vardenafil and their analogs from herbal medicines".Talanta 115(2013):482-489. |
入库方式： OAI收割
来源：兰州化学物理研究所
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