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Genetic history of an archaic hominin group from Denisova Cave in Siberia

文献类型：期刊论文

作者Reich, David1,2,3; Green, Richard E.4,5; Kircher, Martin4; Krause, Johannes4,6; Patterson, Nick2,3; Durand, Eric Y.7; Viola, Bence4,8; Briggs, Adrian W.1,4; Stenzel, Udo4; Johnson, Philip L. F.9
刊名NATURE
出版日期2010-12-23
卷号468期号:7327页码:1053-1060
关键词Neanderthal Genome Mitochondrial-dna Mtdna Sequence Diversity Indonesia Patterns Flores Dates Sima
ISSN号0028-0836
文献子类Article
英文摘要Using DNA extracted from a finger bone found in Denisova Cave in southern Siberia, we have sequenced the genome of an archaic hominin to about 1.9-fold coverage. This individual is from a group that shares a common origin with Neanderthals. This population was not involved in the putative gene flow from Neanderthals into Eurasians; however, the data suggest that it contributed 4-6% of its genetic material to the genomes of present-day Melanesians. We designate this hominin population 'Denisovans' and suggest that it may have been widespread in Asia during the Late Pleistocene epoch. A tooth found in Denisova Cave carries a mitochondrial genome highly similar to that of the finger bone. This tooth shares no derived morphological features with Neanderthals or modern humans, further indicating that Denisovans have an evolutionary history distinct from Neanderthals and modern humans.
URL标识查看原文
WOS关键词NEANDERTHAL GENOME ; MITOCHONDRIAL-DNA ; MTDNA SEQUENCE ; DIVERSITY ; INDONESIA ; PATTERNS ; FLORES ; DATES ; SIMA
WOS研究方向Science & Technology - Other Topics
语种英语
WOS记录号WOS:000285553800049
公开日期2013-11-27
源URL[http://119.78.100.205/handle/311034/4484]  
专题古脊椎动物与古人类研究所_图书馆1
通讯作者reich@genetics.med.harvard.edu; bence.viola@eva.mpg.de; paabo@eva.mpg.de
作者单位1.Harvard Univ, Sch Med, Dept Genet, Boston, MA 02115 USA
2.MIT, Broad Inst, Cambridge, MA 02142 USA
3.Harvard Univ, Cambridge, MA 02142 USA
4.Max Planck Inst Evolutionary Anthropol, Dept Evolutionary Genet, D-04103 Leipzig, Germany
5.Univ Calif Santa Cruz, Dept Biomol Engn, Santa Cruz, CA 95064 USA
6.Univ Tubingen, Inst Nat Wissensch Archaol, D-72070 Tubingen, Germany
7.Univ Calif Berkeley, Dept Integrat Biol, Berkeley, CA 94720 USA
8.Max Planck Inst Evolutionary Anthropol, Dept Human Evolut, D-04103 Leipzig, Germany
9.Emory Univ, Dept Biol, Atlanta, GA 30322 USA
10.Univ Montana, Div Biol Sci, Missoula, MT 59812 USA
推荐引用方式
GB/T 7714		 Reich, David,Green, Richard E.,Kircher, Martin,et al. Genetic history of an archaic hominin group from Denisova Cave in Siberia[J]. NATURE,2010,468(7327):1053-1060.
APA Reich, David.,Green, Richard E..,Kircher, Martin.,Krause, Johannes.,Patterson, Nick.,...&paabo@eva.mpg.de.(2010).Genetic history of an archaic hominin group from Denisova Cave in Siberia.NATURE,468(7327),1053-1060.
MLA Reich, David,et al."Genetic history of an archaic hominin group from Denisova Cave in Siberia".NATURE 468.7327(2010):1053-1060.

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