Sesquiterpenoids from Inula racemosa Hook. f. Inhibit Nitric Oxide Production
文献类型：期刊论文
| 作者 | Zhang, SD ; Qin, JJ ; Jin, HZ ; Yin, YH ; Li, HL ; Yang, XW ; Li, X ; Shan, L ; Zhang, WD |
| 刊名 | PLANTA MEDICA
 |
| 出版日期 | 2012 |
| 卷号 | 78期号:2页码:166-171 |
| 关键词 | Inula racemosa Hook. f. Compositae sesquiterpenes density functional theory nitric oxide |
| ISSN号 | 0032-0943 |
| 通讯作者 | shanleish@yahoo.com.cn ; wdzhangy@hotmail.com |
| 中文摘要 | A novel trinorsesquiterpene (1), three new (2-4), and 10 known sesquiterpenes were isolated from the roots of Inula racemosa Hook. f. The structures and absolute configurations of the new sesquiterpenes were elucidated by extensive spectroscopic and computational methods. All compounds were evaluated for their inhibition of LPS-induced nitric oxide production in RAW264.7 macrophages, and the results indicated that compounds 9, 12, and 13 moderately inhibited nitric oxide production with IC50 values of 7.39 +/- 0.36, 6.35 +/- 0.26, and 5.39 +/- 0.18 mu M, respectively. |
| 学科主题 | Plant Sciences; Chemistry, Medicinal; Pharmacology & Pharmacy |
| 语种 | 英语 |
| 公开日期 | 2013-08-28 |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/10014]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 推荐引用方式 GB/T 7714 | Zhang, SD,Qin, JJ,Jin, HZ,et al. Sesquiterpenoids from Inula racemosa Hook. f. Inhibit Nitric Oxide Production[J]. PLANTA MEDICA,2012,78(2):166-171. |
| APA | Zhang, SD.,Qin, JJ.,Jin, HZ.,Yin, YH.,Li, HL.,...&Zhang, WD.(2012).Sesquiterpenoids from Inula racemosa Hook. f. Inhibit Nitric Oxide Production.PLANTA MEDICA,78(2),166-171. |
| MLA | Zhang, SD,et al."Sesquiterpenoids from Inula racemosa Hook. f. Inhibit Nitric Oxide Production".PLANTA MEDICA 78.2(2012):166-171. |
入库方式： OAI收割
来源：南海海洋研究所
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