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Exploring novel bioactive compounds from marine microbes
文献类型：期刊论文
| 作者 | Zhang, LX ; An, R ; Wang, JP ; Sun, N ; Zhang, S ; Hu, JC ; Kuai, J |
| 刊名 | CURRENT OPINION IN MICROBIOLOGY
 |
| 出版日期 | 2005 |
| 卷号 | 8期号:3页码:276-281 |
| ISSN号 | 1369-5274 |
| 通讯作者 | zhang_lixin@gibh.ac.cn |
| 中文摘要 | The historical paradigm of the deep ocean as a biological 'desert' has shifted to one of a 'rainforest' owing to the isolation of many novel microbes and their associated bioactive compounds. Recently, there has been an explosion of information about novel bioactive compounds that have been isolated from marine microbes in an effort to further explore the relatively untapped marine microbes and their secondary metabolites for drug discovery. The microbes are recovered and purified from the ocean by both conventional and innovative isolation methods to obtain those previously thought to be 'uncultivable'. To overcome the difficulties and limitations associated with cultivation techniques, several DNA-based molecular methods have been developed to bypass the culture-dependent bottleneck. Bioactive compounds isolated using the above strategies have not only shown importance in biotechnological and pharmaceutical applications but have also increased our understanding of the diversity of marine microbiota, ecosystem functions and the exploitable biology. |
| 学科主题 | Microbiology |
| 收录类别 | SCI |
| WOS记录号 | WOS:000230098000007 |
| 公开日期 | 2011-06-29 |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/2241]  |
| 专题 | 南海海洋研究所_广东省海洋药物重点实验室 |
| 推荐引用方式 GB/T 7714 | Zhang, LX,An, R,Wang, JP,et al. Exploring novel bioactive compounds from marine microbes[J]. CURRENT OPINION IN MICROBIOLOGY,2005,8(3):276-281. |
| APA | Zhang, LX.,An, R.,Wang, JP.,Sun, N.,Zhang, S.,...&Kuai, J.(2005).Exploring novel bioactive compounds from marine microbes.CURRENT OPINION IN MICROBIOLOGY,8(3),276-281. |
| MLA | Zhang, LX,et al."Exploring novel bioactive compounds from marine microbes".CURRENT OPINION IN MICROBIOLOGY 8.3(2005):276-281. |
入库方式： OAI收割
来源：南海海洋研究所
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