Antimalarial flavonol glycosides from Euphorbia hirta
文献类型：期刊论文
| 作者 | Liu, Y ; Murakami, N ; Ji, H ; Abreu, P ; Zhang, S |
| 刊名 | PHARMACEUTICAL BIOLOGY
 |
| 出版日期 | 2007 |
| 卷号 | 45期号:4页码:278-281 |
| 关键词 | afzelin antimalarial cytotoxicity euphorbia hirta myricitrin quercitrin |
| ISSN号 | 1388-0209 |
| 通讯作者 | yonghongliu@scsio.ac.cn |
| 中文摘要 | Bioassay-guided fractionation of the MeOH extracts of Euphorbia hirta Linn (Euphorbiaceae) aerial parts led to the isolation of flavonol glycosides afzelin (1), quercitrin (2), and myricitrin (3), whose structures were established by MS and NMR analysis. Compounds 1-3 showed proliferation inhibition of Plasmodium falciparum, with IC50 values of 1.1, 4.1, 5.4 mu g/mL, repectively. On the other hand, they exhibited little cytotoxic property against human epidermoid carcinoma KB 3-1 cells. |
| 学科主题 | Plant Sciences; Medical Laboratory Technology; Pharmacology & Pharmacy |
| 收录类别 | SCI |
| 原文出处 | TAYLOR & FRANCIS INC |
| WOS记录号 | WOS:000247132400005 |
| 公开日期 | 2011-07-03 |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/5232]  |
| 专题 | 南海海洋研究所_广东省海洋药物重点实验室 |
| 推荐引用方式 GB/T 7714 | Liu, Y,Murakami, N,Ji, H,et al. Antimalarial flavonol glycosides from Euphorbia hirta[J]. PHARMACEUTICAL BIOLOGY,2007,45(4):278-281. |
| APA | Liu, Y,Murakami, N,Ji, H,Abreu, P,&Zhang, S.(2007).Antimalarial flavonol glycosides from Euphorbia hirta.PHARMACEUTICAL BIOLOGY,45(4),278-281. |
| MLA | Liu, Y,et al."Antimalarial flavonol glycosides from Euphorbia hirta".PHARMACEUTICAL BIOLOGY 45.4(2007):278-281. |
入库方式： OAI收割
来源：南海海洋研究所
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