Alkaloids from the Stem Bark of Micromelum falcatum
文献类型：期刊论文
| 作者 | Luo, XM ; Qi, SH ; Yin, H ; Gao, CH ; Zhang, S |
| 刊名 | CHEMICAL & PHARMACEUTICAL BULLETIN
 |
| 出版日期 | 2009 |
| 卷号 | 57期号:6页码:600-602 |
| 关键词 | Micromelum falcatum alkaloid quinoldione quinolinone |
| ISSN号 | 0009-2363 |
| 通讯作者 | zhsimd@scsio.ac.cn |
| 中文摘要 | Two new quinoldione alkaloids, methyl 2-(3-hydroxy-1-methyl-2,4-dioxo-1,2,3,4-tetrahydroquinolin-3-yl)acetate (1) and 3-hydroxy-1-methyl-3-(2-oxopropyl)quinoline-2,4(1H,3H)-dione (2), and two quinolinone alkaloids previously synthesized but first isolated as natural products, N-methylflindersine (3) and 4-hydroxy-3-methoxy-1-methyl-2(1H)-quinolinone (4), were isolated from the stem bark of Micromelum falcatum, together with the known N-methylswietenidine-B (5). Their structures were established mainly on the basis of 1D- and 2D-NMR techniques. All compounds were evaluated for toxicity towards brine shrimp larvae, and 3 showed strong toxicity with an LD50 value of 1.39 mu g/ml. |
| 学科主题 | Chemistry, Medicinal; Chemistry, Multidisciplinary; Pharmacology & Pharmacy |
| 收录类别 | SCI |
| 原文出处 | PHARMACEUTICAL SOC JAPAN |
| WOS记录号 | WOS:000266480600011 |
| 公开日期 | 2011-07-03 |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/5326]  |
| 专题 | 南海海洋研究所_广东省海洋药物重点实验室 |
| 推荐引用方式 GB/T 7714 | Luo, XM,Qi, SH,Yin, H,et al. Alkaloids from the Stem Bark of Micromelum falcatum[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,2009,57(6):600-602. |
| APA | Luo, XM,Qi, SH,Yin, H,Gao, CH,&Zhang, S.(2009).Alkaloids from the Stem Bark of Micromelum falcatum.CHEMICAL & PHARMACEUTICAL BULLETIN,57(6),600-602. |
| MLA | Luo, XM,et al."Alkaloids from the Stem Bark of Micromelum falcatum".CHEMICAL & PHARMACEUTICAL BULLETIN 57.6(2009):600-602. |
入库方式： OAI收割
来源：南海海洋研究所
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