Growth-associated biosynthesis of astaxanthin in heterotrophic Chlorella zofingiensis (Chlorophyta)
文献类型：期刊论文
| 作者 | Wang, Y ; Peng, J |
| 刊名 | WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
 |
| 出版日期 | 2008 |
| 卷号 | 24期号:9页码:1915-1922 |
| 关键词 | astaxanthin Chlorella zofingiensis glucose heterotrophic culture |
| ISSN号 | 0959-3993 |
| 通讯作者 | ywang@yic.ac.cn |
| 中文摘要 | The green microalga Chlorella zofingiensis can produce the ketocarotenoid astaxanthin under heterotrophic culture conditions. Here we report the growth-associated biosynthesis of astaxanthin in this biotechnologically important alga. With glucose as sole carbon and energy source, C. zofinginesis grew fast in the dark with rapid exhaustion of nitrogen and carbon sources from media, leading to a high specific growth rate (0.034 h(-1)). Cultures started at a cell concentration of about 3.4 x 10(9) cells l(-1) reached, after 6 days, standing biomass values of 1.6 x 10(11) cells or 8.5 g dry weight l(-1). Surprisingly, the biosynthesis of astaxanthin was found to start at early exponential phase, independent of cessation of cell division. A general trend was observed that the culture conditions benefiting cell growth also benefited astaxanthin accumulation, indicating that astaxanthin was a growth-associated product in this alga. The maximum cell dry biomass and astaxanthin yield were 11.75 g l(-1) and 11.14 mg l(-1) (about 1 mg g(-1)), simultaneously obtained in the fed-batch culture with a combined glucose-nitrate mixture addition, which were the highest ever reported in dark-heterotrophic algal cultures. The possible reasons why dark-heterotrophic C. zofingiensis could produce astaxanthin during the course of cell growth were discussed. |
| 学科主题 | Biotechnology & Applied Microbiology |
| 收录类别 | SCI |
| 原文出处 | SEP |
| WOS记录号 | WOS:000257961500036 |
| 公开日期 | 2011-07-03 |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/5364]  |
| 专题 | 南海海洋研究所_海洋生物 |
| 推荐引用方式 GB/T 7714 | Wang, Y,Peng, J. Growth-associated biosynthesis of astaxanthin in heterotrophic Chlorella zofingiensis (Chlorophyta)[J]. WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY,2008,24(9):1915-1922. |
| APA | Wang, Y,&Peng, J.(2008).Growth-associated biosynthesis of astaxanthin in heterotrophic Chlorella zofingiensis (Chlorophyta).WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY,24(9),1915-1922. |
| MLA | Wang, Y,et al."Growth-associated biosynthesis of astaxanthin in heterotrophic Chlorella zofingiensis (Chlorophyta)".WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY 24.9(2008):1915-1922. |
入库方式： OAI收割
来源：南海海洋研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。