氯磺隆是典型的乙酰胺酸合成酶抑制剂，在酸性条件下主要以中性分子形式存在，其水解反应是准一级的SN2反应；在中性或碱性条件下，主要以阴离子形式存在，水解反应较慢，在土壤中，除化学降解外，微生物降解也是氯磺隆另一重要环境归趋，而光化学降解并非氯磺隆环境归趋的主要方式。

Chlorosulfuron is a typical acetolactate synthase (ALS)inhibitor .Low pH values increase the amount of neutral form of substrate which is more active to hydrolyze , while under basic conditions , the main form of substrate is anion which hydrolyzes very slowly .Chemical
hydrolysis as well as microorgahism degradation is the very important dissipation path of chlorosulfuron dissipation in soil , while photolysis to overall dissipation in the environment is expected to be minor .