Dietary exposure to polychlorinated dibenzo-p-dioxins and dibenzofurans via fish consumption and dioxin-like activity in fish determined by H4IIE-luc bioassay
文献类型：期刊论文
| 作者 | Chan, Janet Kit Yan1,2,3; Man, Yu Bon1,2; Xing, Guan Hua1,2,4; Wu, Sheng Chun1,2,5; Murphy, Margaret B.6; Xu, Ying7; Wong, Ming H.1,2 |
| 刊名 | SCIENCE OF THE TOTAL ENVIRONMENT
 |
| 出版日期 | 2013-10-01 |
| 卷号 | 463页码:1192-1200 |
| 关键词 | PCDD/Fs Electronic waste Estimated daily intake H4IIE-Iuc cell bioassay Freshwater fish |
| ISSN号 | 0048-9697 |
| 通讯作者 | Wong, MH (reprint author), Hong Kong Baptist Univ, Croucher Inst Environm Sci, Room SCT701-712,Cha Chi Ming Sci Tower,Ho Sin Han, Kowloon Tong, Hong Kong, Peoples R China. |
| 中文摘要 | Dietary exposure to polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) via fish consumption in two major electronic (e) waste sites: Guiyu (GY), Guangdong Province and Taizhou (TZ), Zhejiang Province, and dioxin-like activity in fish determined by H4IIE-luc bioassay. In the present study, all fish were below EU's maximum allowable concentration in muscle of fish (4 pg WHO-TEQ/g wet wt), except crucian (4.28 pg WHO-TEQ/g wet wt) and silver carps (7.49 pg WHO-TEQ/g wet wt) collected from GY rivers. Moreover, the residual concentration in bighead carp collected from GY (2.15 pg WHO-TEQ/g wet wt) was close to the EU's action level (3 pg WHO-TEQ/g wet wt) which gives "early warning" to the competent authorities and operators to take measures to eliminate contamination. In addition, results indicated that the maximum human intake of PCDD/Fs via freshwater fish consumption its GY was 4.31 pg WHO-TEQ/kg bw/day, which exceeds the higher end of the tolerable daily intake recommended by the WHO, EC-SCF and JECFA (1-4, 2 and 23 pg WHO-TEO/kg bw/day respectively). Furthermore, H4IIE-luc cell bioassay provides a very sensitive and cost-efficient screening tool for assessing the overall dioxin-like toxicity in the study, and is therefore valuable for high-throughput environmental monitoring studies. (C) 2012 Elsevier B.V. All rights reserved. |
| 英文摘要 | Dietary exposure to polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) via fish consumption in two major electronic (e) waste sites: Guiyu (GY), Guangdong Province and Taizhou (TZ), Zhejiang Province, and dioxin-like activity in fish determined by H4IIE-luc bioassay. In the present study, all fish were below EU's maximum allowable concentration in muscle of fish (4 pg WHO-TEQ/g wet wt), except crucian (4.28 pg WHO-TEQ/g wet wt) and silver carps (7.49 pg WHO-TEQ/g wet wt) collected from GY rivers. Moreover, the residual concentration in bighead carp collected from GY (2.15 pg WHO-TEQ/g wet wt) was close to the EU's action level (3 pg WHO-TEQ/g wet wt) which gives "early warning" to the competent authorities and operators to take measures to eliminate contamination. In addition, results indicated that the maximum human intake of PCDD/Fs via freshwater fish consumption its GY was 4.31 pg WHO-TEQ/kg bw/day, which exceeds the higher end of the tolerable daily intake recommended by the WHO, EC-SCF and JECFA (1-4, 2 and 23 pg WHO-TEO/kg bw/day respectively). Furthermore, H4IIE-luc cell bioassay provides a very sensitive and cost-efficient screening tool for assessing the overall dioxin-like toxicity in the study, and is therefore valuable for high-throughput environmental monitoring studies. (C) 2012 Elsevier B.V. All rights reserved. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Environmental Sciences |
| 研究领域[WOS] | Environmental Sciences & Ecology |
| 关键词[WOS] | WASTE RECYCLING SITE ; POLYCYCLIC AROMATIC-HYDROCARBONS ; POLYBROMINATED DIPHENYL ETHERS ; HEALTH-RISK ASSESSMENT ; HUMAN BREAST-MILK ; FRESH-WATER FISH ; HONG-KONG ; MARINE ORGANISMS ; COASTAL WATERS ; CALUX BIOASSAY |
| 收录类别 | SCI |
| 资助信息 | Research Grants Council of the University Grants Committee of Hong Kong (Central Allocation Group Research Project) [HKBU 1/03C]; Match Fund from Hong Kong Baptist University |
| 语种 | 英语 |
| WOS记录号 | WOS:000325831200130 |
| 公开日期 | 2014-01-06 |
| 源URL | [http://ir.ihb.ac.cn/handle/342005/19604]  |
| 专题 | 水生生物研究所_水环境工程研究中心_期刊论文 |
| 作者单位 | 1.Hong Kong Baptist Univ, Croucher Inst Environm Sci, Kowloon Tong, Hong Kong, Peoples R China 2.Hong Kong Baptist Univ, Dept Biol, Kowloon Tong, Hong Kong, Peoples R China 3.Univ Hong Kong, Sch Biol Sci, Pokfulam, Hong Kong, Peoples R China 4.China Natl Environm Monitoring Ctr, Beijing 100012, Peoples R China 5.City Univ Hong Kong, State Key Lab Marine Pollut, Kowloon, Hong Kong, Peoples R China 6.City Univ Hong Kong, Dept Biol & Chem, Kowloon, Hong Kong, Peoples R China 7.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Hubei Province, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chan, Janet Kit Yan,Man, Yu Bon,Xing, Guan Hua,et al. Dietary exposure to polychlorinated dibenzo-p-dioxins and dibenzofurans via fish consumption and dioxin-like activity in fish determined by H4IIE-luc bioassay[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2013,463:1192-1200. |
| APA | Chan, Janet Kit Yan.,Man, Yu Bon.,Xing, Guan Hua.,Wu, Sheng Chun.,Murphy, Margaret B..,...&Wong, Ming H..(2013).Dietary exposure to polychlorinated dibenzo-p-dioxins and dibenzofurans via fish consumption and dioxin-like activity in fish determined by H4IIE-luc bioassay.SCIENCE OF THE TOTAL ENVIRONMENT,463,1192-1200. |
| MLA | Chan, Janet Kit Yan,et al."Dietary exposure to polychlorinated dibenzo-p-dioxins and dibenzofurans via fish consumption and dioxin-like activity in fish determined by H4IIE-luc bioassay".SCIENCE OF THE TOTAL ENVIRONMENT 463(2013):1192-1200. |
入库方式： OAI收割
来源：水生生物研究所
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