Terpenoids and their anti-HIV-1 activities from Excoecaria acerifolia
文献类型：期刊论文
| 作者 | Huang, Sheng-Zhuo1,4; Zhang, Xuan3; Ma, Qing-Yun1,4; Zheng, Yong-Tang3; Xu, Feng-Qing2; Peng, Hua2 ; Dai, Hao-Fu1,4; Zhou, Jun2; Zhao, You-Xing1,4
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| 刊名 | FITOTERAPIA
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| 出版日期 | 2013-12-01 |
| 卷号 | 91页码:224-230 |
| 关键词 | Excoecaria acerifolia Euphorbiaceae Anti-HIV Diterpenoid Triterpenoid |
| ISSN号 | 0367-326X |
| 通讯作者 | Zhou,J (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650204,Peoples R China.,junzhou3264@126.com ; zhaoyouxing@itbb.org.cn |
| 英文摘要 | Five new diterpenoids named excocarinols A-E (1-5) including three pimaranes, one cleistanthane, and one nor-beyerane, together with nine known compounds, were isolated from the EtOAc extract of the Chinese ethnodrug Gua-jing-ban (Excoecaria acerifolia Didr.). Their structures were elucidated by the analysis of spectroscopic data including 1D, 2D NMR and HR-MS. The anti-HIV-1 bioassay on the diterpenoids showed that excocarinol A (1) exhibited moderate anti-HIV-1 activity with EC50 5.58 mu M and SI (Selection Index) over 112.71. Crown Copyright (C) 2013 Published by Elsevier B.V. All rights reserved. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 学科主题 | Pharmacology & Pharmacy |
| 类目[WOS] | Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Pharmacology & Pharmacy |
| 关键词[WOS] | ISOPIMARANE DITERPENOIDS ; CHEMICAL-CONSTITUENTS ; DAPHNE-ACUTILOBA ; AGALLOCHA ; LEAVES |
| 收录类别 | SCI |
| 资助信息 | Special Fund for Agro-scientific Research in the Public Interest [201303117];National Support Science and Technology Subject [2013BAI11B04];Fundamental Scientific Research Funds for CATAS [1630052013001, ITBB110301] |
| 语种 | 英语 |
| WOS记录号 | WOS:000327574300033 |
| 公开日期 | 2014-01-13 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/17402]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Minist Agr, Key Lab Biol & Genet Resources Trop Crops, Haikou 571101, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China 3.Chinese Acad Sci, Key Lab Anim Models & Human Dis Mech Chinese Acad, Kunming Inst Zool, Kunming 650223, Peoples R China 4.Hainan Key Lab Res & Dev Nat Prod Li Folk Med, Haikou 571101, Peoples R China |
| 推荐引用方式 GB/T 7714 | Huang, Sheng-Zhuo,Zhang, Xuan,Ma, Qing-Yun,et al. Terpenoids and their anti-HIV-1 activities from Excoecaria acerifolia[J]. FITOTERAPIA,2013,91:224-230. |
| APA | Huang, Sheng-Zhuo.,Zhang, Xuan.,Ma, Qing-Yun.,Zheng, Yong-Tang.,Xu, Feng-Qing.,...&Zhao, You-Xing.(2013).Terpenoids and their anti-HIV-1 activities from Excoecaria acerifolia.FITOTERAPIA,91,224-230. |
| MLA | Huang, Sheng-Zhuo,et al."Terpenoids and their anti-HIV-1 activities from Excoecaria acerifolia".FITOTERAPIA 91(2013):224-230. |
入库方式： OAI收割
来源：昆明植物研究所
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