Novel Bioactive Dibenzocyclooctadiene Lignans from Schisandra neglecta
文献类型：期刊论文
| 作者 | Gao, Xue-Mei1,2,3; Niu, De-Yun1,2; Meng, Chun-Yang1,2; Yao, Fu-Quan1,2; Zhou, Bin1,2; Wang, Rui-Rui4; Yang, Liu-Meng4; Zheng, Yong-Tang4; Hu, Qiu-Fen1,2; Sun, Han-Dong3
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| 刊名 | JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
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| 出版日期 | 2013-12-01 |
| 卷号 | 24期号:12页码:2021-+ |
| 关键词 | Schisandra neglecta dibenzocyclooctadiene lignans anti-HIV-1 activities cytotoxicities |
| ISSN号 | 0103-5053 |
| 通讯作者 | Hu,QF (reprint author),Yunnan Univ Nationalities,State Ethn Affairs Commiss,Key Lab Ethn Med Resource Chem,Kunming 650031,Peoples R China. ; huqiufena@aliyun.com ; xwl@mail.kib.ac.cn |
| 英文摘要 | Four new dibenzocyclooctadiene lignans, neglectalignans A-D (1-4), together with nineteen known compounds (5-23) were isolated from the stems of Schisandra neglecta. Their structures and stereochemistries were elucidated by spectroscopic methods, including 1D-, 2D-nuclear magnetic resonance (NMR) and high-resolution electrospray ionization mass spectrometry (HR-ESI-MS) techniques. Compounds 1-4 were evaluated for their anti-HIV activities and cytotoxicities. The results revealed that compounds 1-4 showed moderate anti-HIV-1 activities with therapeutic index (TI) values above 61.7, 22.6, 57.7, and 27.9, respectively, and weak cytotoxic activities for some selected cell lines. |
| WOS标题词 | Science & Technology ; Physical Sciences |
| 类目[WOS] | Chemistry, Multidisciplinary |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | SCHIZANDRA-CHINENSIS BAILL ; ANTI-HIV-1 ACTIVITIES ; CONSTITUENTS ; GOMISIN ; WILSONIANA ; FRUITS |
| 收录类别 | SCI ; IC |
| 资助信息 | NSFYP [2012FB178]; Excellent Scientific and Technological Team of Yunnan High School [2010CI08]; Yunnan University of Nationalities Green Chemistry and Functional Materials Research for Provincial Innovation Team [2011HC008]; Open Research Fund Program of Key Laboratory of Ethnic Medicine Resource Chemistry (Yunnan University of Nationalities) [2010XY08] |
| 语种 | 英语 |
| WOS记录号 | WOS:000328703200017 |
| 公开日期 | 2014-01-21 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/17451]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Yunnan Univ Nationalities, State Ethn Affairs Commiss, Key Lab Ethn Med Resource Chem, Kunming 650031, Peoples R China 2.Minist Educ, Kunming 650031, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China 4.Chinese Acad Sci, Kunming Inst Zool, Kunming 650223, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gao, Xue-Mei,Niu, De-Yun,Meng, Chun-Yang,et al. Novel Bioactive Dibenzocyclooctadiene Lignans from Schisandra neglecta[J]. JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY,2013,24(12):2021-+. |
| APA | Gao, Xue-Mei.,Niu, De-Yun.,Meng, Chun-Yang.,Yao, Fu-Quan.,Zhou, Bin.,...&Xiao, Wei-Lie.(2013).Novel Bioactive Dibenzocyclooctadiene Lignans from Schisandra neglecta.JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY,24(12),2021-+. |
| MLA | Gao, Xue-Mei,et al."Novel Bioactive Dibenzocyclooctadiene Lignans from Schisandra neglecta".JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY 24.12(2013):2021-+. |
入库方式： OAI收割
来源：昆明植物研究所
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