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Bioactive metabolites from macrofungi: ethnopharmacology, biological activities and chemistry
文献类型：期刊论文
| 作者 | De Silva, Dilani D.1,2,3,4,5; Rapior, Sylvie6; Sudarman, Enge7; Stadler, Marc7; Xu, Jianchu1,2 ; Alias, S. Aisyah8; Hyde, Kevin D.1,2,3,4
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| 刊名 | FUNGAL DIVERSITY
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| 出版日期 | 2013-09-01 |
| 卷号 | 62期号:1页码:1-40 |
| 关键词 | Medicinal mushrooms Anti-oxidant Anti-tumor Anti-HIV Anti-microbial Anti-viral Hypocholesterolemic Anti-diabetic Anti-Alzheimer Anti-malarial Food supplements |
| ISSN号 | 1560-2745 |
| 通讯作者 | Xu,JC (reprint author),Chinese Acad Sci,Key Lab Plant Biodivers & Biogeog East Asia KLPB,Kunming Inst Bot,Kunming 650201,Yunnan,Peoples R China.,j.c.xu@cgiar.org ; kdhyde3@gmail.com |
| 英文摘要 | Exploration of natural sources for novel bioactive compounds has been an emerging field of medicine over the past decades, providing drugs or lead compounds of considerable therapeutic potential. This research has provided exciting evidence on the isolation of microbe-derived metabolites having prospective biological activities. Mushrooms have been valued as traditional sources of natural bioactive compounds for many centuries and have been targeted as promising therapeutic agents. Many novel biologically active compounds have been reported as a result of research on medicinal mushrooms. In this review, we compile the information on bioactive structure-elucidated metabolites from macrofungi discovered over the last decade and highlight their unique chemical diversity and potential benefits to novel drug discovery. The main emphasis is on their anti-Alzheimer, anti-diabetic, anti-malarial, anti-microbial, anti-oxidant, anti-tumor, anti-viral and hypocholesterolemic activities which are important medicinal targets in terms of drug discovery today. Moreover, the reader's attention is brought to focus on mushroom products and food supplements available in the market with claimed biological activities and potential human health benefits. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 学科主题 | Mycology |
| 类目[WOS] | Mycology |
| 研究领域[WOS] | Mycology |
| 关键词[WOS] | MUSHROOM PLEUROTUS-OSTREATUS ; TG-APPSWE/PS1DE9 MOUSE MODEL ; FUNGUS PHELLINUS-IGNIARIUS ; BREAST-CANCER CELLS ; GANODERIC ACID ME ; REVERSE-TRANSCRIPTASE INHIBITORS ; BASIDIOMYCETE HEXAGONIA-SPECIOSA ; RESISTANT STAPHYLOCOCCUS-AUREUS ; DEPRIVATION-INDUCED APOPTOSIS ; ANTITUMOR-PROMOTING ACTIVITY |
| 收录类别 | SCI |
| 资助信息 | French-Thai cooperation PHC SIAM [1551, 25587RA];Mae Fah Luang University [MFU/54 1 01 02 00 48];project "Value added products from basidiomycetes: Putting Thailand's biodiversity to use" [BRN049/2553];National Research Council of Thailand (NRCT) [NRCT/55201020007];Thailand Research Fund [BRG 5580009];University Malaya [CG037-2013, RG203-12SUS] |
| 语种 | 英语 |
| WOS记录号 | WOS:000326929100001 |
| 公开日期 | 2014-01-13 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/17433]  |
| 专题 | 昆明植物研究所_资源植物与生物技术所级重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Plant Biodivers & Biogeog East Asia KLPB, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China 2.East Asia Node, World Agroforestry Ctr, Beijing, Peoples R China 3.Mae Fah Luang Univ, Inst Excellence Fungal Res, Chiang Rai 57100, Thailand 4.Mae Fah Luang Univ, Sch Sci, Chiang Rai 57100, Thailand 5.Univ Peradeniya, Dept Bot, Fac Sci, Peradeniya 20500, Sri Lanka 6.Univ Montpellier I, Lab Bot Phytochem & Mycol, Fac Pharm, UMR 5175,CEFE, F-34093 Montpellier 5, France 7.Helmhotz Ctr Infect Res, Dept Microbial Drugs, Braunschweig, Germany 8.Univ Malaya, Inst Ocean & Earth Sci, Kuala Lumpur 50603, Malaysia |
| 推荐引用方式 GB/T 7714 | De Silva, Dilani D.,Rapior, Sylvie,Sudarman, Enge,et al. Bioactive metabolites from macrofungi: ethnopharmacology, biological activities and chemistry[J]. FUNGAL DIVERSITY,2013,62(1):1-40. |
| APA | De Silva, Dilani D..,Rapior, Sylvie.,Sudarman, Enge.,Stadler, Marc.,Xu, Jianchu.,...&Hyde, Kevin D..(2013).Bioactive metabolites from macrofungi: ethnopharmacology, biological activities and chemistry.FUNGAL DIVERSITY,62(1),1-40. |
| MLA | De Silva, Dilani D.,et al."Bioactive metabolites from macrofungi: ethnopharmacology, biological activities and chemistry".FUNGAL DIVERSITY 62.1(2013):1-40. |
入库方式： OAI收割
来源：昆明植物研究所
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