中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Acylated iridoid glycosides and acylated rhamnopyranoses from Gmelina arborea flowers

文献类型:期刊论文

作者Gu, Wei1,2; Hao, Xiao-Jiang3; Liu, Hong-Xin1,2; Wang, Yue-Hu1; Long, Chun-Lin1,4
刊名PHYTOCHEMISTRY LETTERS
出版日期2013-11-01
卷号6期号:4页码:681-685
关键词Gmelina arborea Iridoid glycosides Acylated rhamnopyranoses Phenylethanoid Cytoprotective activity
ISSN号1874-3900
通讯作者Long,CL (reprint author),Minzu Univ China,Coll Life & Environm Sci,Beijing 100081,Peoples R China.,wangyuehu@mail.kib.ac.cn ; long@mail.kib.ac.cn
英文摘要Nine acylated iridoid glycosides (1-9), five acylated rhamnopyranoses (10-14) and verbascoside (15) were isolated from Gmelina arborea flowers, including 5 new compounds (1, 2, and 10-12). The cytoprotective activity of 11 selected compounds (1-8, 10, 11, and 15) against CCl4-induced cytotoxicity on liver was determined. Compounds 1, 2, 4, 7, 8 and 15 displayed hepatoprotective activity. 6-O-alpha-L-(2 '',3 ''-di-O-trans-p-hydroxycinnamoyl)rhamnopyranosylcatalpol (2) exhibited the most potent cytoprotective effect with an EC50 value of 42.5 mu M (SI = 19.3) compared with biphenyldimethylesterate (DDB, EC50 = 277.3 mu M, SI = 9.8) and bicylo-ethanol (EC50 = 279.2 mu M, SI = 12.2). Among the acylated iridoid glycosides, the compounds (2 and 8) containing phenolic hydroxy groups were more active than were those lacking them. (C) 2013 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
WOS标题词Science & Technology ; Life Sciences & Biomedicine
学科主题Biochemistry & Molecular Biology ; Plant Sciences
类目[WOS]Biochemistry & Molecular Biology ; Plant Sciences
研究领域[WOS]Biochemistry & Molecular Biology ; Plant Sciences
关键词[WOS]PREMNA-JAPONICA ; ANTIFUNGAL ACTIVITY ; LEAVES ; HEARTWOOD ; LIGNANS ; LINN ; 6-O-ALPHA-L-RHAMNOPYRANOSYLCATALPOL ; CONSTITUENTS
收录类别SCI
语种英语
WOS记录号WOS:000325872700038
公开日期2014-01-13
源URL[http://ir.kib.ac.cn/handle/151853/17435]  
专题昆明植物研究所_资源植物与生物技术所级重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, Key Lab Econ Plants & Biotechnol, Kunming 650201, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
4.Minzu Univ China, Coll Life & Environm Sci, Beijing 100081, Peoples R China
推荐引用方式
GB/T 7714
Gu, Wei,Hao, Xiao-Jiang,Liu, Hong-Xin,et al. Acylated iridoid glycosides and acylated rhamnopyranoses from Gmelina arborea flowers[J]. PHYTOCHEMISTRY LETTERS,2013,6(4):681-685.
APA Gu, Wei,Hao, Xiao-Jiang,Liu, Hong-Xin,Wang, Yue-Hu,&Long, Chun-Lin.(2013).Acylated iridoid glycosides and acylated rhamnopyranoses from Gmelina arborea flowers.PHYTOCHEMISTRY LETTERS,6(4),681-685.
MLA Gu, Wei,et al."Acylated iridoid glycosides and acylated rhamnopyranoses from Gmelina arborea flowers".PHYTOCHEMISTRY LETTERS 6.4(2013):681-685.

入库方式: OAI收割

来源:昆明植物研究所

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