Biomimetically inspired total synthesis of (12S)-12-hydroxymonocerin and (12R)-12-hydroxymonocerin
文献类型：期刊论文
| 作者 | Fang BW(方博文)1; Xie XG(谢新刚)1; Jing P(靖鹏)1; Zhao CG(赵常贵)1; Li HL(李辉林)1; Ma, Haichen1; She XG(厍学功)1,2 |
| 刊名 | Tetrahedron
 |
| 出版日期 | 2013 |
| 卷号 | 69期号:51页码:11025-11030 |
| 关键词 | Biomimetically inspired total synthesis cis-Fused furobenzopyranone (12S)-12-Hydroxymonocerin (12R)-12-Hydroxymonocerin Anion Relay Chemistry |
| ISSN号 | 0040-4020 |
| 通讯作者 | 厍学功 |
| 英文摘要 | A concise asymmetric total synthesis of (12S)-12-hydroxymonocerin (1) and (12R)-12-hydroxymonocerin (2) were efficiently achieved from the known 4-bromo-2,6-dimethoxyphenol. The synthetic approach was inspired by our biomimetic synthesis of (+)-monocerin (3) and 7-O-demethylmonocerin (4). The cis-fused furobenzopyranones of 1 and 2 was efficiently constructed via an intramolecular nucleophilic trapping of a quinonemethide intermediate, which was obtained by benzylic oxidation of compound 10 using 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone (DDQ). |
| 学科主题 | 物理化学与绿色催化 |
| 收录类别 | SCI |
| 资助信息 | the NSFC (21125207;21102062;21072086);the MOST (2010CB833203);PCSIRT (IRT1138);the FRFCU (lzujbky-2013-49;lzujbky-2013-ct02);Program 111 |
| 语种 | 英语 |
| WOS记录号 | WOS:000328808300027 |
| 公开日期 | 2014-01-06 |
| 源URL | [http://210.77.64.217/handle/362003/4979]  |
| 专题 | 兰州化学物理研究所_OSSO国家重点实验室 |
| 作者单位 | 1.Lanzhou Univ, Dept Chem, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China |
| 推荐引用方式 GB/T 7714 | Fang BW,Xie XG,Jing P,et al. Biomimetically inspired total synthesis of (12S)-12-hydroxymonocerin and (12R)-12-hydroxymonocerin[J]. Tetrahedron,2013,69(51):11025-11030. |
| APA | Fang BW.,Xie XG.,Jing P.,Zhao CG.,Li HL.,...&She XG.(2013).Biomimetically inspired total synthesis of (12S)-12-hydroxymonocerin and (12R)-12-hydroxymonocerin.Tetrahedron,69(51),11025-11030. |
| MLA | Fang BW,et al."Biomimetically inspired total synthesis of (12S)-12-hydroxymonocerin and (12R)-12-hydroxymonocerin".Tetrahedron 69.51(2013):11025-11030. |
入库方式： OAI收割
来源：兰州化学物理研究所
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