Blood coagulation resistance of nonwoven single-walled carbon nanotubes and its implications for implantable prostheses
文献类型：期刊论文
| 作者 | Jie, M ; Li, S ; Hua, K ; Wang, CY ; Guo, XT ; Xu, HY ; Xie, SS |
| 刊名 | NEW CARBON MATERIALS
 |
| 出版日期 | 2004 |
| 卷号 | 19期号:3页码:166 |
| 关键词 | FIBRINOGEN BIOCOMPATIBILITY |
| ISSN号 | 1007-8827 |
| 通讯作者 | Xu, HY: Chinese Acad Med Sci, Inst Basic Med, Beijing 100005, Peoples R China. |
| 中文摘要 | The anticoagulation property of a SWNT membrane is investigated in blood-contacting environments. The adsorption behaviors of fibrinogen, albumin and fresh plasma on SWNT membrane were investigated by scanning electron microscopy (SEM) and energy dispersive X-ray analysis. The platelet adhesion and activation induced by the SWNT membrane were evaluated through SEM observations and fluorescent labeled flow cytometric analysis. Results indicated that the SWNT membrane showed a clear adsorption preference of fibrinogen over albumin. However, there was no appreciable platelet adhesion and activation occurred consequently on a SWNT membrane surface pre-absorbed with fresh plasma, and the percentage of activated platelets caused by a SWNT membrane in a platelet-rich-plasma was about 5%. The conclusion is that the SWNT membrane has unique platelet inertness in blood environments and this anticoagulant effect permits potential use in artificial organs, prostheses and tissue engineering in the cardiac-vascular systems. |
| 收录类别 | SCI |
| 语种 | 中文 |
| 公开日期 | 2013-09-17 |
| 源URL | [http://ir.iphy.ac.cn/handle/311004/34272]  |
| 专题 | 物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文 |
| 推荐引用方式 GB/T 7714 | Jie, M,Li, S,Hua, K,et al. Blood coagulation resistance of nonwoven single-walled carbon nanotubes and its implications for implantable prostheses[J]. NEW CARBON MATERIALS,2004,19(3):166. |
| APA | Jie, M.,Li, S.,Hua, K.,Wang, CY.,Guo, XT.,...&Xie, SS.(2004).Blood coagulation resistance of nonwoven single-walled carbon nanotubes and its implications for implantable prostheses.NEW CARBON MATERIALS,19(3),166. |
| MLA | Jie, M,et al."Blood coagulation resistance of nonwoven single-walled carbon nanotubes and its implications for implantable prostheses".NEW CARBON MATERIALS 19.3(2004):166. |
入库方式： OAI收割
来源：物理研究所
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