Brownian dynamics simulation of directional sliding of histone octamers caused by DNA bending
文献类型：期刊论文
| 作者 | Li, W ; Dou, SX ; Xie, P ; Wang, PY |
| 刊名 | PHYSICAL REVIEW E
 |
| 出版日期 | 2006 |
| 卷号 | 73期号:5 |
| 关键词 | INDIVIDUAL NUCLEOSOMES CHROMATIN CORE DISRUPTION RESOLUTION REVEALS COMPLEX RSC |
| ISSN号 | 1539-3755 |
| 通讯作者 | Wang, PY: Chinese Acad Sci, Inst Phys, Lab Soft Matter Phys, Beijing Natl Lab Condensed Matter Phys, Beijing 100080, Peoples R China. |
| 中文摘要 | Chromatin-remodeling complexes such as SWI/SNF and RSC of yeast can perturb the structure of nucleosomes in an ATP-dependent manner. Experimental results prove that this chromatin remodeling process involves DNA bending. We simulate the effect of DNA bending, caused by chromatin-remodeling complexes, on directional sliding of histone octamers by Brownian dynamics simulation. The simulation results show that, after a DNA loop being generated at the side of a nucleosome, the histone octamer slides towards this DNA loop until the loop disappears. The DNA loop size is an important factor affecting the process of directional sliding of the histone octamer. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2013-09-17 |
| 源URL | [http://ir.iphy.ac.cn/handle/311004/34354]  |
| 专题 | 物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文 |
| 推荐引用方式 GB/T 7714 | Li, W,Dou, SX,Xie, P,et al. Brownian dynamics simulation of directional sliding of histone octamers caused by DNA bending[J]. PHYSICAL REVIEW E,2006,73(5). |
| APA | Li, W,Dou, SX,Xie, P,&Wang, PY.(2006).Brownian dynamics simulation of directional sliding of histone octamers caused by DNA bending.PHYSICAL REVIEW E,73(5). |
| MLA | Li, W,et al."Brownian dynamics simulation of directional sliding of histone octamers caused by DNA bending".PHYSICAL REVIEW E 73.5(2006). |
入库方式： OAI收割
来源：物理研究所
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