Direct methods beyond small-molecule crystallography
文献类型：期刊论文
| 作者 | Fan, HF |
| 刊名 | PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE
 |
| 出版日期 | 2010 |
| 卷号 | 207期号:12页码:2621 |
| 关键词 | RESOLUTION ELECTRON-MICROSCOPY ANOMALOUS SCATTERING DATA SINGLE ISOMORPHOUS REPLACEMENT COMBINING DIRECT-METHODS INCOMMENSURATE MODULATED STRUCTURES X-RAY-ANALYSIS JOINT PROBABILITY-DISTRIBUTION CRYSTAL-STRUCTURE SOLUTION PHASE DETERMINATION STRUCTURE REFINEMENT |
| ISSN号 | 1862-6300 |
| 通讯作者 | Fan, HF: CAS, Beijing Natl Lab Condensed Matter Phys, Inst Phys, Beijing 100190, Peoples R China. |
| 中文摘要 | The development of direct methods outside their traditional field began since the middle 1960s. New applications were explored gradually in four directions. They are the transition of: (i) from single crystals to powder samples, (ii) from X-ray crystallography to electronmicroscopy (EM), (iii) from periodic structures to incommensurate structures and (iv) from small molecules to macromolecular structures. The research on methods of solving crystal structures at the Institute of Physics in Beijing has been focused on the last three directions. The transition of direct methods from X-ray crystallography to EM led to a two-step image processing technique in high-resolution electron microscopy (HREM). This technique combines information of EM and that of electron diffraction (ED) revealing the structure of minute crystals that are unsuitable for X-ray diffraction analysis. The transition of direct methods from periodic crystal structures to incommensurate structures led to the multi-dimensional direct methods enabling ab initio solution of incommensurate modulated structures and composite structures without relying on an assumed modulation model or even the known basic structure. Finally the combination of direct methods with traditional protein crystallographic methods has greatly enhanced the ability of solving protein structures. (C) 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim |
| 收录类别 | SCI |
| 资助信息 | Chinese Academy of Sciences; National Natural Science Foundation of China; National Basic Research Program of China |
| 语种 | 英语 |
| 公开日期 | 2013-09-17 |
| 源URL | [http://ir.iphy.ac.cn/handle/311004/36031]  |
| 专题 | 物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文 |
| 推荐引用方式 GB/T 7714 | Fan, HF. Direct methods beyond small-molecule crystallography[J]. PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE,2010,207(12):2621. |
| APA | Fan, HF.(2010).Direct methods beyond small-molecule crystallography.PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE,207(12),2621. |
| MLA | Fan, HF."Direct methods beyond small-molecule crystallography".PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE 207.12(2010):2621. |
入库方式： OAI收割
来源：物理研究所
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