Direct-method-aided phasing of MAD data
文献类型：期刊论文
| 作者 | Gu, YX ; Liu, YD ; Hao, Q ; Ealick, SE ; Fan, HF |
| 刊名 | ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
 |
| 出版日期 | 2001 |
| 卷号 | 57页码:250 |
| 关键词 | ANOMALOUS SCATTERING DATA COMBINING DIRECT METHODS ISOMORPHOUS REPLACEMENT ANGSTROM RESOLUTION PROTEIN |
| ISSN号 | 0907-4449 |
| 通讯作者 | Fan, HF: Chinese Acad Sci, Inst Phys, POB 603, Beijing 100080, Peoples R China. |
| 中文摘要 | The direct methods of breaking the phase ambiguity intrinsic in one-wavelength anomalous scattering (OAS) data and MAD phasing are powerful methods in their own rights. In a different context, in addition to their success in phasing OAS data, direct methods can also be useful in the treatment of MAD data. The idea has been tested with the MAD data at 2.5 Angstrom resolution from the protein human adenosine kinase [Mathews et al. (1998), Biochemistry, 37, 15607-15620]. The results showed that the incorporation of direct methods in MAD phasing led to a significant improvement of phases over those obtained from the conventional MAD phasing method alone, as indicated by improved map correlation coefficients (with the existing model), reduced phase errors by 4.5 degrees and improved map connectivity. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2013-09-17 |
| 源URL | [http://ir.iphy.ac.cn/handle/311004/36108]  |
| 专题 | 物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文 |
| 推荐引用方式 GB/T 7714 | Gu, YX,Liu, YD,Hao, Q,et al. Direct-method-aided phasing of MAD data[J]. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY,2001,57:250. |
| APA | Gu, YX,Liu, YD,Hao, Q,Ealick, SE,&Fan, HF.(2001).Direct-method-aided phasing of MAD data.ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY,57,250. |
| MLA | Gu, YX,et al."Direct-method-aided phasing of MAD data".ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 57(2001):250. |
入库方式： OAI收割
来源：物理研究所
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