Effect of alamethicin on the structure of lipid bilayers
文献类型：期刊论文
| 作者 | Li, DP ; Hu, SX ; Mai, ZH ; Li, M |
| 刊名 | HIGH ENERGY PHYSICS AND NUCLEAR PHYSICS-CHINESE EDITION
 |
| 出版日期 | 2005 |
| 卷号 | 29页码:1 |
| 关键词 | ANTIMICROBIAL PEPTIDES MEMBRANE INCLUSIONS ION CHANNELS MECHANISM ORIENTATION SCATTERING INSERTION MELITTIN FORCES |
| ISSN号 | 0254-3052 |
| 通讯作者 | Li, DP: Chinese Acad Sci, Inst Phys, POB 603, Beijing 100080, Peoples R China. |
| 中文摘要 | Alamethicin is a 20-amino acid membrane-active peptide from the fungus Trichoderma viride that spontaneously inserts into lipid membranes and self-associates into transmembrane channels. It has an antimicrobial activity against fungi and Gram-positive bacteria. We have investigated the effect of the peptide on the structure of lipid membranes by X-ray scattering method. The highly aligned stacks of membranes were prepared by evaporation of organic solutions of alamethicin and 1,2-dioleoyl-sn-glycero-3-phosphocholine deposited on clean silicon surfaces and were immersed in excess ultra pure water. The in-situ X-ray measurements show that the membranes with inserted peptides become thinner and softer at high molar peptide/lipid ratio. |
| 收录类别 | SCI |
| 语种 | 中文 |
| 公开日期 | 2013-09-17 |
| 源URL | [http://ir.iphy.ac.cn/handle/311004/36342]  |
| 专题 | 物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文 |
| 推荐引用方式 GB/T 7714 | Li, DP,Hu, SX,Mai, ZH,et al. Effect of alamethicin on the structure of lipid bilayers[J]. HIGH ENERGY PHYSICS AND NUCLEAR PHYSICS-CHINESE EDITION,2005,29:1. |
| APA | Li, DP,Hu, SX,Mai, ZH,&Li, M.(2005).Effect of alamethicin on the structure of lipid bilayers.HIGH ENERGY PHYSICS AND NUCLEAR PHYSICS-CHINESE EDITION,29,1. |
| MLA | Li, DP,et al."Effect of alamethicin on the structure of lipid bilayers".HIGH ENERGY PHYSICS AND NUCLEAR PHYSICS-CHINESE EDITION 29(2005):1. |
入库方式： OAI收割
来源：物理研究所
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