Effect of Laser Field and Mechanical Force on Deoxyribonucleic Acid Melting
文献类型:期刊论文
作者 | Pan, BY ; Zhang, LY ; Dou, SX ; Wang, PY |
刊名 | CHINESE PHYSICS LETTERS
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出版日期 | 2010 |
卷号 | 27期号:7 |
关键词 | DNA DUPLEX STABILITY DENATURATION SEQUENCE MODEL MOLECULES LENGTH |
ISSN号 | 0256-307X |
通讯作者 | Zhang, LY: Chinese Acad Sci, Key Lab Soft Matter Phys, Beijing Natl Lab Condensed Matter Phys, Inst Phys, Beijing 100190, Peoples R China. |
中文摘要 | We propose a physics method to study the effect of laser field and mechanical force on the melting process of double-stranded deoxyribonucleic acid (DNA). A two-dimensional lattice model is established for DNA molecules stuck on the surface, and the stretching energy of the hydrogen bond and stacking energy for each DNA molecule are calculated by using a nonlinear potential. A real-time algorithm is employed to deal with the dynamics process of DNA melting. Numerical results explain the experimental observations. The spatial distribution of the laser field determines the sequences of DNA melting. The simulation has shown the dependence of the final number of melted DNA on the laser field and mechanical force. |
收录类别 | SCI |
资助信息 | National Natural Science Foundation of China [10834014, 10674173, 30770517]; National Basic Research Program of China [2009CB930704] |
语种 | 英语 |
公开日期 | 2013-09-17 |
源URL | [http://ir.iphy.ac.cn/handle/311004/36469] ![]() |
专题 | 物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文 |
推荐引用方式 GB/T 7714 | Pan, BY,Zhang, LY,Dou, SX,et al. Effect of Laser Field and Mechanical Force on Deoxyribonucleic Acid Melting[J]. CHINESE PHYSICS LETTERS,2010,27(7). |
APA | Pan, BY,Zhang, LY,Dou, SX,&Wang, PY.(2010).Effect of Laser Field and Mechanical Force on Deoxyribonucleic Acid Melting.CHINESE PHYSICS LETTERS,27(7). |
MLA | Pan, BY,et al."Effect of Laser Field and Mechanical Force on Deoxyribonucleic Acid Melting".CHINESE PHYSICS LETTERS 27.7(2010). |
入库方式: OAI收割
来源:物理研究所
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