Forces-induced pinpoint denaturation of short DNA
文献类型：期刊论文
| 作者 | Pan, BY ; Zhang, LY ; Dou, SX ; Wang, PY |
| 刊名 | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
 |
| 出版日期 | 2009 |
| 卷号 | 388期号:1页码:137 |
| 关键词 | SINGLE-MOLECULE FRET DUPLEX STABILITY SEQUENCE STACKING PROTEIN LENGTH MODEL |
| ISSN号 | 0006-291X |
| 通讯作者 | Zhang, LY: Chinese Acad Sci, Inst Phys, Lab Soft Matter Phys, Beijing Natl Lab Condensed Matter Phys, 56,8 S 3rd St, Beijing 100190, Peoples R China. |
| 中文摘要 | A method that can pinpoint control DNA denaturation is reported. In the single molecule experiment using spFRET, DNA adhered on a quartz surface is acted upon by both a weak laser field force and a fast temporal mechanical force. The experiment showed that increasing strengths of laser power result in increasing percentage of denatured DNA; different mechanical forces produce different numbers of DNA opening. Besides the method's simplicity and convenience for DNA melting, its crucial advantage and potential application is the ability to denature DNA at specified locations, i.e., a weak laser and a fast temporal mechanical force can be used in pinpoint denaturation of short DNA. (C) 2009 Elsevier Inc. All rights reserved. |
| 收录类别 | SCI |
| 资助信息 | National Natural Science Foundation of China [10834014, 10674173, 30770517]; National Basic Research Program of China [2009CB930704] |
| 语种 | 英语 |
| 公开日期 | 2013-09-17 |
| 源URL | [http://ir.iphy.ac.cn/handle/311004/38328]  |
| 专题 | 物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文 |
| 推荐引用方式 GB/T 7714 | Pan, BY,Zhang, LY,Dou, SX,et al. Forces-induced pinpoint denaturation of short DNA[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2009,388(1):137. |
| APA | Pan, BY,Zhang, LY,Dou, SX,&Wang, PY.(2009).Forces-induced pinpoint denaturation of short DNA.BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,388(1),137. |
| MLA | Pan, BY,et al."Forces-induced pinpoint denaturation of short DNA".BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 388.1(2009):137. |
入库方式： OAI收割
来源：物理研究所
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