Formation of DNA toroids inside confined droplets adsorbed on mica surfaces
文献类型：期刊论文
| 作者 | Hou, XM ; Li, W ; Dou, SX ; Zhang, LY ; Xie, P ; Wang, WC ; Wang, PY |
| 刊名 | PHYSICAL REVIEW E
 |
| 出版日期 | 2009 |
| 卷号 | 79期号:5 |
| 关键词 | MULTIVALENT CATIONS CONDENSATION EJECTION FORCE BACTERIOPHAGE FLUCTUATIONS MICROSCOPY PHAGE |
| ISSN号 | 1539-3755 |
| 通讯作者 | Hou, XM: Chinese Acad Sci, Lab Soft Matter Phys, Beijing Natl Lab Condensed Matter Phys, Inst Phys, Beijing 100190, Peoples R China. |
| 中文摘要 | We report observations of in vitro DNA compaction into toroids in the absence of any condensing agent. The DNA toroid formation is induced by geometry confinement from microdroplets on mica surfaces. With AFM imaging we show that the confined DNA molecules may take the form of random coils or semiordered folded loops with large microdroplets, while they readily take the form of compact and ordered toroids when the microdroplet sizes are small enough. To better understand these phenomena, we carried out coarse-grained Brownian dynamics simulation, obtaining results that were in good agreement with the experimental observations. The simulation reveals that the toroid formation is sensitive to not only the microdroplet size, but also the DNA stiffness. |
| 收录类别 | SCI |
| 资助信息 | National Natural Science Foundation of China [10834014, 10674173, 30770517]; National Basic Research Program of China (973 Program) [2009CB930704] |
| 语种 | 英语 |
| 公开日期 | 2013-09-17 |
| 源URL | [http://ir.iphy.ac.cn/handle/311004/38394]  |
| 专题 | 物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文 |
| 推荐引用方式 GB/T 7714 | Hou, XM,Li, W,Dou, SX,et al. Formation of DNA toroids inside confined droplets adsorbed on mica surfaces[J]. PHYSICAL REVIEW E,2009,79(5). |
| APA | Hou, XM.,Li, W.,Dou, SX.,Zhang, LY.,Xie, P.,...&Wang, PY.(2009).Formation of DNA toroids inside confined droplets adsorbed on mica surfaces.PHYSICAL REVIEW E,79(5). |
| MLA | Hou, XM,et al."Formation of DNA toroids inside confined droplets adsorbed on mica surfaces".PHYSICAL REVIEW E 79.5(2009). |
入库方式： OAI收割
来源：物理研究所
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