Inactivation of A549 cancer cells by a helium-oxygen plasma needle
文献类型：期刊论文
| 作者 | Chen, W ; Huang, J ; Li, H ; Lv, GH ; Wang, XQ ; Zhang, GP ; Wang, PY ; Yang, SZ |
| 刊名 | ACTA PHYSICA SINICA
 |
| 出版日期 | 2012 |
| 卷号 | 61期号:18 |
| 关键词 | PRESSURE DISCHARGE TORCH |
| ISSN号 | 1000-3290 |
| 通讯作者 | Chen, W: Chinese Acad Sci, Inst Phys, Beijing Natl Lab Condensed Matter Phys, Key Lab Soft Matter Phys, Beijing 100190, Peoples R China. |
| 中文摘要 | An inactivation mechanism of A549 cancer cells is studied by using a dielectric barrier discharge (DBD) plasma needle. The influence of oxygen concentration, which is injected into helium plasma afterglow region through a stainless steel tube, is investigated. The neutral red uptake assay provides a qualitative observation of morphological differences between the dead cells and the viable cells after plasma treatment and a quantitative estimation of cell viability under different conditions. In the treatment process at a fixed power of 24 W, the inactivation efficiency of helium-oxygen plasma depends mainly on the exposure time and percentage of added oxygen in helium plasma. Experimental results show that the best parameters of the process are 150 s treatment time, 800 mL/min He with 3% O-2 addition and separation of needle-to-sample 3 mm. According to the helium-oxygen emission spectra of the plasma jet, it is concluded that the reactive species (for example, OH and O) in the helium-oxygen plasma play a major role in the cell deactivation. |
| 收录类别 | SCI |
| 资助信息 | National Natural Science Foundation of China [11005151] |
| 语种 | 中文 |
| 公开日期 | 2013-09-17 |
| 源URL | [http://ir.iphy.ac.cn/handle/311004/39732]  |
| 专题 | 物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文 |
| 推荐引用方式 GB/T 7714 | Chen, W,Huang, J,Li, H,et al. Inactivation of A549 cancer cells by a helium-oxygen plasma needle[J]. ACTA PHYSICA SINICA,2012,61(18). |
| APA | Chen, W.,Huang, J.,Li, H.,Lv, GH.,Wang, XQ.,...&Yang, SZ.(2012).Inactivation of A549 cancer cells by a helium-oxygen plasma needle.ACTA PHYSICA SINICA,61(18). |
| MLA | Chen, W,et al."Inactivation of A549 cancer cells by a helium-oxygen plasma needle".ACTA PHYSICA SINICA 61.18(2012). |
入库方式： OAI收割
来源：物理研究所
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