Intrinsic peroxidase-like activity of ferromagnetic nanoparticles
文献类型：期刊论文
| 作者 | Gao, LZ ; Zhuang, J ; Nie, L ; Zhang, JB ; Zhang, Y ; Gu, N ; Wang, TH ; Feng, J ; Yang, DL ; Perrett, S ; Yan, X |
| 刊名 | NATURE NANOTECHNOLOGY
 |
| 出版日期 | 2007 |
| 卷号 | 2期号:9页码:577 |
| ISSN号 | 1748-3387 |
| 中文摘要 | Nanoparticles containing magnetic materials, such as magnetite ( Fe3O4), are particularly useful for imaging and separation techniques. As these nanoparticles are generally considered to be biologically and chemically inert, they are typically coated with metal catalysts, antibodies or enzymes to increase their functionality as separation agents. Here, we report that magnetite nanoparticles in fact possess an intrinsic enzyme mimetic activity similar to that found in natural peroxidases, which are widely used to oxidize organic substrates in the treatment of wastewater or as detection tools. Based on this finding, we have developed a novel immunoassay in which antibody-modified magnetite nanoparticles provide three functions: capture, separation and detection. The stability, ease of production and versatility of these nanoparticles makes them a powerful tool for a wide range of potential applications in medicine, biotechnology and environmental chemistry. |
| 收录类别 | SCI |
| 公开日期 | 2013-09-18 |
| 源URL | [http://ir.iphy.ac.cn/handle/311004/40215]  |
| 专题 | 物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文 |
| 推荐引用方式 GB/T 7714 | Gao, LZ,Zhuang, J,Nie, L,et al. Intrinsic peroxidase-like activity of ferromagnetic nanoparticles[J]. NATURE NANOTECHNOLOGY,2007,2(9):577. |
| APA | Gao, LZ.,Zhuang, J.,Nie, L.,Zhang, JB.,Zhang, Y.,...&Yan, X.(2007).Intrinsic peroxidase-like activity of ferromagnetic nanoparticles.NATURE NANOTECHNOLOGY,2(9),577. |
| MLA | Gao, LZ,et al."Intrinsic peroxidase-like activity of ferromagnetic nanoparticles".NATURE NANOTECHNOLOGY 2.9(2007):577. |
入库方式： OAI收割
来源：物理研究所
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