Kinetics of Single DNA Compaction by Hexaammine Cobalt Chloride
文献类型：期刊论文
| 作者 | Fu, WB ; Chen, H ; Li, M ; Yan, J |
| 刊名 | JOURNAL OF COMPUTATIONAL AND THEORETICAL NANOSCIENCE
 |
| 出版日期 | 2010 |
| 卷号 | 7期号:1页码:213 |
| 关键词 | MULTIVALENT CATIONS GIANT DNA CONDENSATION MOLECULES MICROSCOPY ELASTICITY DYNAMICS BEADS |
| ISSN号 | 1546-1955 |
| 通讯作者 | Fu, WB: Chinese Acad Sci, Inst Phys, Beijing Natl Lab Condensed Matter Phys, POB 603, Beijing 100080, Peoples R China. |
| 中文摘要 | Stepwise folding and unfolding dynamics of compaction of single DNAs by multivalent cations has been observed in recent single-molecule experiments. The causes of the stepwise signals, however, have not been carefully investigated Using stochastic dynamical simulation algorism, we predict the time courses of changes in the extension of a single DNA subject to various tensions based on a spool model proposed recently. Compared with single-molecule experiments performed using a magnetic tweezer at the same forces, we find that the spool model is in reasonable agreement with the folding dynamics, but not in agreement with the unfolding dynamics The disagreement of the unfolding dynamics can be remedied if some rare, long waiting time events are removed from the unfolding time courses. The implications of the experiments are discussed. |
| 收录类别 | SCI |
| 资助信息 | Ministry of Education of Singapore [R144000171101]; National Natural Science Foundation of China [30870590] |
| 语种 | 英语 |
| 公开日期 | 2013-09-18 |
| 源URL | [http://ir.iphy.ac.cn/handle/311004/40470]  |
| 专题 | 物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文 |
| 推荐引用方式 GB/T 7714 | Fu, WB,Chen, H,Li, M,et al. Kinetics of Single DNA Compaction by Hexaammine Cobalt Chloride[J]. JOURNAL OF COMPUTATIONAL AND THEORETICAL NANOSCIENCE,2010,7(1):213. |
| APA | Fu, WB,Chen, H,Li, M,&Yan, J.(2010).Kinetics of Single DNA Compaction by Hexaammine Cobalt Chloride.JOURNAL OF COMPUTATIONAL AND THEORETICAL NANOSCIENCE,7(1),213. |
| MLA | Fu, WB,et al."Kinetics of Single DNA Compaction by Hexaammine Cobalt Chloride".JOURNAL OF COMPUTATIONAL AND THEORETICAL NANOSCIENCE 7.1(2010):213. |
入库方式： OAI收割
来源：物理研究所
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