Magnetization behavior and magnetic viscosity in nanostructured PrCo(4.5)C(0.5) ribbons
文献类型：期刊论文
| 作者 | Yang, B ; Shen, BG ; Zhao, TY ; Sun, JR |
| 刊名 | JOURNAL OF APPLIED PHYSICS
 |
| 出版日期 | 2008 |
| 卷号 | 103期号:12 |
| ISSN号 | 0021-8979 |
| 关键词 | PERMANENT-MAGNETS ENERGY |
| 通讯作者 | Shen, BG: Chinese Acad Sci, Inst Phys, State Key Lab Magnetism, Beijing 100190, Peoples R China. |
| 中文摘要 | RecQ family helicases, functioning as caretakers of genomic integrity, contain a zinc-binding motif which is highly conserved among these helicases, but does not have a substantial structural similarity with any other known zinc-finger folds. In the present study, we show that a truncated variant of the human RECQ5 beta helicase comprised of the conserved helicase domain only, a splice variant named RECQ5 alpha, possesses neither ATPase nor DNA-unwinding activities, but surprisingly displays a strong strand-annealing activity. In contrast, fragments of RECQ5 beta including the intact zinc-binding motif, which is located immediately downstream of the helicase domain, exhibit much reduced strand-annealing activity but are proficient in DNA unwinding. Quantitative measurements indicate that the regulatory role of the zinc-binding motif is achieved by enhancing the DNA-binding affinity of the enzyme. The novel intramolecular modulation of RECQ5 catalytic activity mediated by the zinc-binding motif may represent a universal regulation mode for all RecQ family helicases. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2013-09-18 |
| 源URL | [http://ir.iphy.ac.cn/handle/311004/41576]  |
| 专题 | 物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文 |
| 推荐引用方式 GB/T 7714 | Yang, B,Shen, BG,Zhao, TY,et al. Magnetization behavior and magnetic viscosity in nanostructured PrCo(4.5)C(0.5) ribbons[J]. JOURNAL OF APPLIED PHYSICS,2008,103(12). |
| APA | Yang, B,Shen, BG,Zhao, TY,&Sun, JR.(2008).Magnetization behavior and magnetic viscosity in nanostructured PrCo(4.5)C(0.5) ribbons.JOURNAL OF APPLIED PHYSICS,103(12). |
| MLA | Yang, B,et al."Magnetization behavior and magnetic viscosity in nanostructured PrCo(4.5)C(0.5) ribbons".JOURNAL OF APPLIED PHYSICS 103.12(2008). |
入库方式： OAI收割
来源：物理研究所
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