Model for helicase translocating along single-stranded DNA and unwinding double-stranded DNA
文献类型：期刊论文
| 作者 | Xie, P |
| 刊名 | BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
 |
| 出版日期 | 2006 |
| 卷号 | 1764期号:11页码:1719 |
| 关键词 | HEPATITIS-C VIRUS COLI REP HELICASE N-TERMINAL DOMAIN CRYSTAL-STRUCTURE ACTIVE MECHANISM RECBCD ENZYME DUPLEX DNA ATP SEPARATION COMPLEXES |
| ISSN号 | 1570-9639 |
| 通讯作者 | Xie, P: Zhejiang Sci Tech Univ, Dept Phys, Xiasha Coll Pk, Hangzhou 310018, Zhejiang, Peoples R China. |
| 中文摘要 | A model is proposed for non-hexameric helicases translocating along single-stranded (ss) DNA and unwinding double-stranded (ds) DNA. The translocation of a monomeric helicase along ssDNA in weakly-ssDNA-bound state is driven by the Stokes force that is resulted from the conformational change following the transition of the nucleotide state. The unwinding of dsDNA is resulted mainly from the bending of ssDNA induced by the strong binding force of helicase with dsDNA. The interaction force between ssDNA and helicases in weakly-ssDNA-bound state determines whether monomeric helicases such as PcrA can unwind dsDNA or dimeric helicases such as Rep are required to unwind dsDNA. (c) 2006 Elsevier B.V. All rights reserved. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2013-09-18 |
| 源URL | [http://ir.iphy.ac.cn/handle/311004/42203]  |
| 专题 | 物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文 |
| 推荐引用方式 GB/T 7714 | Xie, P. Model for helicase translocating along single-stranded DNA and unwinding double-stranded DNA[J]. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS,2006,1764(11):1719. |
| APA | Xie, P.(2006).Model for helicase translocating along single-stranded DNA and unwinding double-stranded DNA.BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS,1764(11),1719. |
| MLA | Xie, P."Model for helicase translocating along single-stranded DNA and unwinding double-stranded DNA".BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS 1764.11(2006):1719. |
入库方式： OAI收割
来源：物理研究所
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