Thermodynamic Origins of Shear Band Formation and the Universal Scaling Law of Metallic Glass Strength
文献类型：期刊论文
| 作者 | Liu, YH ; Liu, CT ; Wang, WH ; Inoue, A ; Sakurai, T ; Chen, MW |
| 刊名 | PHYSICAL REVIEW LETTERS
 |
| 出版日期 | 2009 |
| 卷号 | 103期号:6 |
| 关键词 | TEMPERATURE RISE PLASTIC-FLOW FRACTURE COMPRESSION ALLOY DEFORMATION TRANSITION PRESSURE |
| ISSN号 | 0031-9007 |
| 通讯作者 | Chen, MW (reprint author), Tohoku Univ, WPI Adv Inst Mat Res, Sendai, Miyagi 9808577, Japan. |
| 中文摘要 | The fidelity of DNA synthesis by DNA polymerase is significantly increased by a mechanism of proofreading that is performed at the exonuclease active site separate from the polymerase active site. Thus, the transition of DNA between the two active sites is an important activity of DNA polymerase. Here, based on our proposed model, the rates of DNA transition between the two active sites are theoretically studied. With the relevant parameters, which are determined from the available crystal structure and other experimental data, the calculated transfer rate of correctly base-paired DNA from the polymerase to exonuclease sites and the transfer rate after incorporation of a mismatched base are in good agreement with the available experimental data. The transfer rates in the presence of two and three mismatched bases are also consistent with the previous experimental data. In addition, the calculated transfer rate from the exonuclease to polymerase sites has a large value even with the high binding affinity of 3'-5' ssDNA for the exonuclease site, which is also consistent with the available experimental value. Moreover, we also give some predictive results for the transfer rate of DNA containing only A:T base pairs and that of DNA containing only G:C base pairs. (C) 2009 Elsevier Ltd. All rights reserved. |
| 收录类别 | SCI |
| 资助信息 | JSPS; Global COE; Tohoku University; "World Premier International (WPI) Center Initiative," MEXT, Japan; Division of Materials Science and Engineering; Office of Basic Energy Sciences; U.S. Department of Energy; Hong Kong Polytechnic University; NSFC [50731008]; MOST 973 [2007CB613904] |
| 语种 | 英语 |
| 公开日期 | 2013-09-23 |
| 源URL | [http://ir.iphy.ac.cn/handle/311004/45781]  |
| 专题 | 物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文 |
| 推荐引用方式 GB/T 7714 | Liu, YH,Liu, CT,Wang, WH,et al. Thermodynamic Origins of Shear Band Formation and the Universal Scaling Law of Metallic Glass Strength[J]. PHYSICAL REVIEW LETTERS,2009,103(6). |
| APA | Liu, YH,Liu, CT,Wang, WH,Inoue, A,Sakurai, T,&Chen, MW.(2009).Thermodynamic Origins of Shear Band Formation and the Universal Scaling Law of Metallic Glass Strength.PHYSICAL REVIEW LETTERS,103(6). |
| MLA | Liu, YH,et al."Thermodynamic Origins of Shear Band Formation and the Universal Scaling Law of Metallic Glass Strength".PHYSICAL REVIEW LETTERS 103.6(2009). |
入库方式： OAI收割
来源：物理研究所
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