Using single-walled carbon nanotubes nonwoven films as scaffolds to enhance long-term cell proliferation in vitro
文献类型：期刊论文
| 作者 | Meng, J ; Song, L ; Meng, J ; Kong, H ; Zhu, GJ ; Wang, CY ; Xu, LH ; Xie, SS ; Xu, HY |
| 刊名 | JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
 |
| 出版日期 | 2006 |
| 卷号 | 79A期号:2页码:298 |
| 关键词 | POLYMER-DEMIXED NANOTOPOGRAPHY TOPOGRAPHY FUNCTIONALIZATION |
| ISSN号 | 1549-3296 |
| 通讯作者 | Xu, HY (reprint author), Chinese Acad Med Sci, Inst Basic Med, Dept Biomed Engn, Beijing 100005, Peoples R China. |
| 中文摘要 | Carbon nanotabes have attracted intensive interests in biomedical research in recent years. In this study, a novel type of carbon nanotubes material so called nonwoven single-walled carbon nanotubes (SWNTs) with nanotopographic structure and macroscopic volume was used as cell growing scaffold. The morphology and surface chemistry of nonwoven SWNTs were observed and characterized through scanning electron microscopy and X-ray photoelectron spectroscopy, respectively. The cells were cultivated in nonwoven SWNTs and in other types of substrate as control. The cells growth behaviors including adhesion, protiferation, and cytoskeletal development was investigated by using cell viability assay and confocal observation. The experimental results indicated that nonwoven SWNTs exhibited significant enhancement to the cells adhesion and proliferation in at least 3 weeks. Numerous and highly organized cytoskeletal structures were observed when the cells were cultured in nonwoven SWNTs. Furthermore, an obvious promotional influence of the cells cultivated in nonwoven SWNTs scaffold upon the proliferation of those growing in the other kind of substrate through cell-cell communication had been found. The results obtained in this work are of significance to in vitro cell amplification in large scale, tissue regeneration, or guided repair, as well as biomedical device application. (c) 2006 Wiley Periodicals, Inc. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2013-09-23 |
| 源URL | [http://ir.iphy.ac.cn/handle/311004/46468]  |
| 专题 | 物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文 |
| 推荐引用方式 GB/T 7714 | Meng, J,Song, L,Meng, J,et al. Using single-walled carbon nanotubes nonwoven films as scaffolds to enhance long-term cell proliferation in vitro[J]. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A,2006,79A(2):298. |
| APA | Meng, J.,Song, L.,Meng, J.,Kong, H.,Zhu, GJ.,...&Xu, HY.(2006).Using single-walled carbon nanotubes nonwoven films as scaffolds to enhance long-term cell proliferation in vitro.JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A,79A(2),298. |
| MLA | Meng, J,et al."Using single-walled carbon nanotubes nonwoven films as scaffolds to enhance long-term cell proliferation in vitro".JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A 79A.2(2006):298. |
入库方式： OAI收割
来源：物理研究所
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