Structural changes induced by microalloying in Cu46Zr47-xAl7Gdx metallic glasses
文献类型：期刊论文
| 作者 | Xi, XK ; Sandor, MT ; Liu, YH ; Wang, WH ; Wu, Y |
| 刊名 | SCRIPTA MATERIALIA
 |
| 出版日期 | 2009 |
| 卷号 | 61期号:10页码:967 |
| 关键词 | FORMING ABILITY ATOMIC PACKING ALLOYS PLASTICITY LIQUID NMR ZR |
| ISSN号 | 1359-6462 |
| 通讯作者 | Wu, Y (reprint author), Univ N Carolina, Dept Phys & Astron, Chapel Hill, NC 27599 USA. |
| 中文摘要 | Circadian KaiC phosphorylation in cyanobacteria reconstituted in vitro recently initiates a series of studies experimentally and theoretically to explore its mechanism. In this paper, we report a dynamic diversity in hexameric KaiC phosphoforms using a multi-layer reaction network based on the nonequivalence of the dual phosphorylation sites (S431 and T432) in each KaiC subunit. These diverse oscillatory profiles can generate a kaleidoscopic phase modulation pattern probably responsible for the genome-wide transcription rhythms directly and/or indirectly in cyanobacteria. Particularly, our model reveals that a single KaiC hexamer is an energy-based, phosphorylation-dependent and self-regulated circadian oscillator modulated by KaiA and KaiB. We suggest that T432 is the main regulator for the oscillation amplitude, while S431 is the major phase regulator. S431 and T432 coordinately control the phosphorylation period. Robustness of the Kai network was examined by mixing samples in different phases, and varying protein concentrations and temperature. Similar results were obtained regardless of the deterministic or stochastic method employed. Therefore, the dynamic diversities and robustness of Kai oscillator make it a qualified core pacemaker that controls the cellular processes in cyanobacteria pervasively and accurately. |
| 收录类别 | SCI |
| 资助信息 | US Army Research Office [W911NF-09-1-0343]; National Science Foundation of China [50621061]; Chinese Academy of Sciences |
| 语种 | 英语 |
| 公开日期 | 2013-09-24 |
| 源URL | [http://ir.iphy.ac.cn/handle/311004/53275]  |
| 专题 | 物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文 |
| 推荐引用方式 GB/T 7714 | Xi, XK,Sandor, MT,Liu, YH,et al. Structural changes induced by microalloying in Cu46Zr47-xAl7Gdx metallic glasses[J]. SCRIPTA MATERIALIA,2009,61(10):967. |
| APA | Xi, XK,Sandor, MT,Liu, YH,Wang, WH,&Wu, Y.(2009).Structural changes induced by microalloying in Cu46Zr47-xAl7Gdx metallic glasses.SCRIPTA MATERIALIA,61(10),967. |
| MLA | Xi, XK,et al."Structural changes induced by microalloying in Cu46Zr47-xAl7Gdx metallic glasses".SCRIPTA MATERIALIA 61.10(2009):967. |
入库方式： OAI收割
来源：物理研究所
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