Study of interactions between DNA and histone with molecular combing method
文献类型:期刊论文
作者 | Liu, YY ; Don, SX ; Wang, PY ; Xie, P ; Wang, WC |
刊名 | ACTA PHYSICA SINICA
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出版日期 | 2005 |
卷号 | 54期号:2页码:622 |
关键词 | ATOMIC-FORCE MICROSCOPY FLUORESCENCE MICROSCOPY NUCLEOSOME FORMATION ELASTICITY MENISCUS MOTION |
ISSN号 | 1000-3290 |
通讯作者 | Liu, YY (reprint author), Chinese Acad Sci, Lab Soft Matter Phys, Beijing 100080, Peoples R China. |
中文摘要 | The interactions between DNA and histone are studied by using the molecular combing method. With this simple but effective method, X-DNA molecules are stretched to a length of 26-28 part, 1.6-1.7 times of their contour length (similar to 16.2 mum). After DNA binding of histones, DNA molecules are condensed and the lengths of the stretched complexes become significantly shorter, with length distribution peak lying between 10-14 mum. The lengths of the stretched DNA-histone complexes are closely related to the histone concentration and the mixing ratio of DNA base pair and dye molecule. |
收录类别 | SCI |
语种 | 中文 |
公开日期 | 2013-09-24 |
源URL | [http://ir.iphy.ac.cn/handle/311004/53760] ![]() |
专题 | 物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文 |
推荐引用方式 GB/T 7714 | Liu, YY,Don, SX,Wang, PY,et al. Study of interactions between DNA and histone with molecular combing method[J]. ACTA PHYSICA SINICA,2005,54(2):622. |
APA | Liu, YY,Don, SX,Wang, PY,Xie, P,&Wang, WC.(2005).Study of interactions between DNA and histone with molecular combing method.ACTA PHYSICA SINICA,54(2),622. |
MLA | Liu, YY,et al."Study of interactions between DNA and histone with molecular combing method".ACTA PHYSICA SINICA 54.2(2005):622. |
入库方式: OAI收割
来源:物理研究所
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