A novel glucose colorimetric sensor based on intrinsic peroxidase-like activity of C-60-carboxyfullerenes
文献类型：期刊论文
| 作者 | Li, RM ; Zhen, MM ; Guan, MR ; Chen, DQ ; Zhang, GQ ; Ge, JC ; Gong, P ; Wang, CR ; Shu, CY |
| 刊名 | BIOSENSORS & BIOELECTRONICS
 |
| 出版日期 | 2013 |
| 卷号 | 47页码:502 |
| 关键词 | C-60-carboxyfullerenes Peroxidase-like activity Colorimetric sensor Glucose |
| ISSN号 | 0956-5663 |
| 通讯作者 | Ge, JC (reprint author), Chinese Acad Sci, Tech Inst Phys & Chem, Beijing 100190, Peoples R China. |
| 中文摘要 | C-60-carboxyfullerene, C-60[C(COOH)(2)](2), has been proven to function as peroxidase mimetics that can catalyze the reaction of peroxidase substrate 3,3',5,5'-tetramethylbenzidine (TMB) in the presence of H2O2 to produce a blue color reaction. Kinetic studies further indicate that C-60[C(COOH)(2)](2) has an even higher affinity to TMB than that of the natural enzyme, horseradish peroxidase (HRP). C-60[C(COOH)(2)](2)/glucose oxidase (GO(x))/TMB system provides a novel colorimetric sensor for glucose and shows good response toward glucose detection over a range of 1.0-40 mu M with a limit of detection 0.5 mu M (3 sigma/slope). Moreover, this sensitive and selective sensor can be successfully applied for the quantitative determination of glucose in human serum. The results indicate that it is a simple, cheap, convenient, highly selective, sensitive, and easy handling colorimetric assay. (C) 2013 Elsevier B.V. All rights reserved. |
| 资助信息 | 973 Program [2011CB302100]; National Natural Science Foundation of China [21121063, 91027018, 51172244]; NSAF [11076027] |
| 语种 | 英语 |
| 公开日期 | 2014-01-16 |
| 源URL | [http://ir.iphy.ac.cn/handle/311004/56731]  |
| 专题 | 物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文 |
| 推荐引用方式 GB/T 7714 | Li, RM,Zhen, MM,Guan, MR,et al. A novel glucose colorimetric sensor based on intrinsic peroxidase-like activity of C-60-carboxyfullerenes[J]. BIOSENSORS & BIOELECTRONICS,2013,47:502. |
| APA | Li, RM.,Zhen, MM.,Guan, MR.,Chen, DQ.,Zhang, GQ.,...&Shu, CY.(2013).A novel glucose colorimetric sensor based on intrinsic peroxidase-like activity of C-60-carboxyfullerenes.BIOSENSORS & BIOELECTRONICS,47,502. |
| MLA | Li, RM,et al."A novel glucose colorimetric sensor based on intrinsic peroxidase-like activity of C-60-carboxyfullerenes".BIOSENSORS & BIOELECTRONICS 47(2013):502. |
入库方式： OAI收割
来源：物理研究所
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