High Surface-Enhanced Raman Scattering Performance of Individual Gold Nanoflowers and Their Application in Live Cell Imaging
文献类型:期刊论文
作者 | Li, Q ; Jiang, YY ; Han, RC ; Zhong, XL ; Liu, SY ; Li, ZY ; Sha, YL ; Xu, DS |
刊名 | SMALL
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出版日期 | 2013 |
卷号 | 9期号:6页码:927 |
关键词 | gold nanoflowers surface-enhanced Raman scattering Raman imaging live cell imaging |
ISSN号 | 1613-6810 |
通讯作者 | Li, ZY (reprint author), Chinese Acad Sci, Inst Phys, Lab Opt Phys, Beijing 100190, Peoples R China. |
中文摘要 | Molecular imaging techniques based on surface-enhanced Raman scattering (SERS) face a lack of reproducibility and reliability, thus hampering its practical application. Flower-like gold nanoparticles have strong SERS enhancement performance due to having plenty of hot-spots on their surfaces, and this enhancement is not dependent on the aggregation of the particles. These features make this kind of particle an ideal SERS substrate to improve the reproducibility in SERS imaging. Here, the SERS properties of individual flower-like gold nanoparticles are systematically investigated. The measurements reveal that the enhancement of a single gold nanoparticle is independent of the polarization of the excitation laser with an enhancement factor as high as 108. After capping with Raman signal molecules and folic acid, the gold nanoflowers show strong Raman signal in the living cells, excellent targeting properties, and a high signal-to-noise ratio for SERS imaging. |
资助信息 | NSFC [50821061, 21073007, 20973008, 11104342]; MSTC (NKBRSF) [2011CB808702, 2007CB936201, 2013CB632704] |
语种 | 英语 |
公开日期 | 2014-01-16 |
源URL | [http://ir.iphy.ac.cn/handle/311004/57070] ![]() |
专题 | 物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文 |
推荐引用方式 GB/T 7714 | Li, Q,Jiang, YY,Han, RC,et al. High Surface-Enhanced Raman Scattering Performance of Individual Gold Nanoflowers and Their Application in Live Cell Imaging[J]. SMALL,2013,9(6):927. |
APA | Li, Q.,Jiang, YY.,Han, RC.,Zhong, XL.,Liu, SY.,...&Xu, DS.(2013).High Surface-Enhanced Raman Scattering Performance of Individual Gold Nanoflowers and Their Application in Live Cell Imaging.SMALL,9(6),927. |
MLA | Li, Q,et al."High Surface-Enhanced Raman Scattering Performance of Individual Gold Nanoflowers and Their Application in Live Cell Imaging".SMALL 9.6(2013):927. |
入库方式: OAI收割
来源:物理研究所
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