In vitro and in vivo studies on biodegradable CaMgZnSrYb high-entropy bulk metallic glass
文献类型：期刊论文
| 作者 | Li, HF ; Xie, XH ; Zhao, K ; Wang, YB ; Zheng, YF ; Wang, WH ; Qin, L |
| 刊名 | ACTA BIOMATERIALIA
 |
| 出版日期 | 2013 |
| 卷号 | 9期号:10页码:8561 |
| 关键词 | Ca20Mg20Zn20Sr20Yb20 alloy High-entropy alloys Bulk metallic glasses Biodegradable metals Bone |
| ISSN号 | 1742-7061 |
| 通讯作者 | Zheng, YF (reprint author), Peking Univ, State Key Lab Turbulence & Complex Syst, Beijing 100871, Peoples R China. |
| 中文摘要 | In order to enhance the corrosion resistance of the Ca65Mg15Zn20 bulk metallic glass, which has too fast a degradation rate for biomedical applications, we fabricated the Ca20Mg20Zn20Sr20Yb20 high-entropy bulk metallic glass because of the unique properties of high-entropy alloys. Our results showed that the mechanical properties and corrosion behavior were enhanced. The in vitro tests showed that the Ca20Mg20Zn20Sr20Yb20 high-entropy bulk metallic glass could stimulate the proliferation and differentiation of cultured osteoblasts. The in vivo animal tests showed that the Ca20Mg20Zn20Sr20Yb20 high-entropy bulk metallic glass did not show any obvious degradation after 4 weeks of implantation, and they can promote osteogenesis and new bone formation after 2 weeks of implantation. The improved mechanical properties and corrosion behavior can be attributed to the different chemical composition as well as the formation of a unique high-entropy atomic structure with a maximum degree of disorder. (C) 2013 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved. |
| 资助信息 | National. Basic Research Program of China (973 Program) [2012CB619102]; National Science Fund for Distinguished Young Scholars [51225101]; National Natural Science Foundation of China [31170909]; Research Fund for the Doctoral Program of Higher Education [20100001110011]; Natural Science Foundation of Heilongjiang Province [ZD201012]; Guangdong Province innovation RD team project [201001C0104669453] |
| 语种 | 英语 |
| 公开日期 | 2014-01-16 |
| 源URL | [http://ir.iphy.ac.cn/handle/311004/57105]  |
| 专题 | 物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文 |
| 推荐引用方式 GB/T 7714 | Li, HF,Xie, XH,Zhao, K,et al. In vitro and in vivo studies on biodegradable CaMgZnSrYb high-entropy bulk metallic glass[J]. ACTA BIOMATERIALIA,2013,9(10):8561. |
| APA | Li, HF.,Xie, XH.,Zhao, K.,Wang, YB.,Zheng, YF.,...&Qin, L.(2013).In vitro and in vivo studies on biodegradable CaMgZnSrYb high-entropy bulk metallic glass.ACTA BIOMATERIALIA,9(10),8561. |
| MLA | Li, HF,et al."In vitro and in vivo studies on biodegradable CaMgZnSrYb high-entropy bulk metallic glass".ACTA BIOMATERIALIA 9.10(2013):8561. |
入库方式： OAI收割
来源：物理研究所
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