Diastereoisomer- and Enantiomer-Specific Accumulation, Depuration, and Bioisomerization of Hexabromocyclododecanes in Zebrafish (Danio rerio)
文献类型：期刊论文
| 作者 | Du Miaomiao ; Lin Lifeng ; Yan Changzhou ; Zhang Xian |
| 刊名 | Environmental Science & Technology
 |
| 出版日期 | 2012-09-10 |
| 卷号 | 46期号:20页码:11040-11046 |
| 英文摘要 | In this study, zebrafish (Danio rerio) were exposed to two dietary concentrations of individual HBCD diastereoisomers (α-, β-, and γ-HBCD) for 42 days,followed by clean food for 21 days, to examine bioaccumulation, depuration, and enantiomer fractions (EFs) of HBCD diastereoisomers and to test the bioisomerization of HBCDs in fish. The depuration of α-, β-, and γ-HBCD in zebrafish followed the first-order process. Bioaccumulation parameters of the three diastereoisomers differed between low and high dose, suggesting that the bioaccumulation of them is concentration dependent. Calculated assimilation efficiencies (AEs), biomagnification factors (BMFs), and half-lives (t1/2) of α-HBCD were the highest among the three diastereoisomers. Furthermore, the study showed that zebrafish could biotransform γ-HBCD to α-HBCD. The highest AE, BMF, and t1/2 of α-HBCD and bioisomerization of γ-HBCD to α-HBCD could explain why α-HBCD appears to be dominant in biota samples. The EFs for α- and γ-HBCD in zebrafish estimated at different times of bioaccumulation and depuration were all significantly greater than those in corresponding food (P < 0.05), indicating selective enrichment of (+) α-enantiomer and (+) γ-enantiomer relative to (−) α-enantiomer and (−) γ-enantiomer, respectively. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2013-08-28 |
| 源URL | [http://124.16.167.195/handle/335003/1157]  |
| 专题 | 城市环境研究所_城市水环境过程与生态风险评价研究组_期刊论文 |
| 推荐引用方式 GB/T 7714 | Du Miaomiao,Lin Lifeng,Yan Changzhou,et al. Diastereoisomer- and Enantiomer-Specific Accumulation, Depuration, and Bioisomerization of Hexabromocyclododecanes in Zebrafish (Danio rerio)[J]. Environmental Science & Technology,2012,46(20):11040-11046. |
| APA | Du Miaomiao,Lin Lifeng,Yan Changzhou,&Zhang Xian.(2012).Diastereoisomer- and Enantiomer-Specific Accumulation, Depuration, and Bioisomerization of Hexabromocyclododecanes in Zebrafish (Danio rerio).Environmental Science & Technology,46(20),11040-11046. |
| MLA | Du Miaomiao,et al."Diastereoisomer- and Enantiomer-Specific Accumulation, Depuration, and Bioisomerization of Hexabromocyclododecanes in Zebrafish (Danio rerio)".Environmental Science & Technology 46.20(2012):11040-11046. |
入库方式： OAI收割
来源：城市环境研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。