Different Impacts of Short-Chain Fatty Acids on Saturated and Polyunsaturated Fatty Acid Biosynthesis in Aurantiochytrium sp
文献类型：期刊论文
| 作者 | Song, X. ; Tan, Y. ; Liu, Y. ; Zhang, J. ; Liu, G. ; Feng, Y. ; & Cui, Q. |
| 刊名 | SD116. J Agric Food Chem
 |
| 出版日期 | 2013 |
| 卷号 | 61期号:41页码:9876-9881 |
| 关键词 | Aurantiochytrium docosahexaenoic acid fatty acid synthase malic enzyme polyketide synthase |
| 中文摘要 | Aurantiochytrium is an important docosahexaenoic acid (DHA) producer containing two kinds of fatty acid synthesis pathways, that is, the fatty acid synthase pathway (FAS) for saturated fatty acid synthesis and the polyketide synthase pathway (PKS) for polyunsaturated fatty acid synthesis. To understand the regulation mechanism between the two pathways, the impacts of six short-chain fatty acids on the fatty acid synthesis of Aurantiochytrium sp. SD116 were studied. All short-chain fatty acids showed little effect on the cell growth, but some of them significantly affected lipid accumulation and fatty acid composition. Pentanoic acid and isovaleric acid greatly inhibited the synthesis of saturated fatty acids, whereas the polyunsaturated fatty acid synthesis was not affected. Analysis of malic enzyme activity, which supplied NADPH for saturated fatty acids biosynthesis, indicated that the two fatty acid synthesis pathways can utilize different substrates and possess independent sources of NADPH. |
| 学科主题 | 代谢物组学 |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2014-03-24 |
| 源URL | [http://ir.qibebt.ac.cn:8080/handle/337004/1683]  |
| 专题 | 青岛生物能源与过程研究所_代谢物组学团队 |
| 推荐引用方式 GB/T 7714 | Song, X.,Tan, Y.,Liu, Y.,et al. Different Impacts of Short-Chain Fatty Acids on Saturated and Polyunsaturated Fatty Acid Biosynthesis in Aurantiochytrium sp[J]. SD116. J Agric Food Chem,2013,61(41):9876-9881. |
| APA | Song, X..,Tan, Y..,Liu, Y..,Zhang, J..,Liu, G..,...&& Cui, Q..(2013).Different Impacts of Short-Chain Fatty Acids on Saturated and Polyunsaturated Fatty Acid Biosynthesis in Aurantiochytrium sp.SD116. J Agric Food Chem,61(41),9876-9881. |
| MLA | Song, X.,et al."Different Impacts of Short-Chain Fatty Acids on Saturated and Polyunsaturated Fatty Acid Biosynthesis in Aurantiochytrium sp".SD116. J Agric Food Chem 61.41(2013):9876-9881. |
入库方式： OAI收割
来源：青岛生物能源与过程研究所
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