Polycyclic Polyprenylated Acylphloroglucinols and Cytotoxic Constituents of Hypericum androsaemum
文献类型：期刊论文
| 作者 | Wang, Kou1,2; Wang, Yuan-Yuan1; Gao, Xiu1; Chen, Xuan-Qin1,2; Peng, Li-Yan1; Li, Yan1 ; Xu, Gang1; Zhao, Qin-Shi1
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| 刊名 | CHEMISTRY & BIODIVERSITY
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| 出版日期 | 2012-06-01 |
| 卷号 | 9期号:6页码:1213-1220 |
| ISSN号 | 1612-1872 |
| 关键词 | Hypericum androsaemum Androforin A Hyperandrone A Cytotoxic activity |
| 通讯作者 | Xu, G (reprint author), Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China,xugang008@mail.kib.ac.cn ; qinshizhao@mail.kib.ac.cn |
| 英文摘要 | Two new polycyclic polyprenylated acylphloroglucinols (PPAPs), androforin A and hyperandrone A (1 and 2, resp.), together with twelve known compounds, were isolated from the aerial parts of Hypericum androsaemum. Their structures were established by detailed spectral analysis. In the cytotoxic assay, 1,4-O-diferuloylsecoisolariciresinol (3) showed activities comparable with those of cisplatin, and acetyloleanolic acid (4) exhibited moderate inhibitory effects against HL-60, SMMC-7721, A-549, MCF-7, and SW480 cancer cell lines. |
| 学科主题 | Biochemistry & Molecular Biology ; Chemistry |
| 类目[WOS] | Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Chemistry |
| 关键词[WOS] | HUILES ESSENTIELLES DHYPERICUM ; ETUDE CHIMIO-TAXONOMIQUE ; ST-JOHNS-WORT ; GENRE HYPERICUM ; DERIVATIVES ; APOPTOSIS ; XANTHONE ; TRITERPENOIDS ; PERFORATUM ; GLUCOSIDES |
| 资助信息 | This work was supported by the National Basic Research Program of China (973 Program, No. 2009CB522300) and the National Science Foundation of China (No. 20972167), and the Foundation from CAS (Xibuzhiguang to G. Xu). |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000305282600019 |
| 公开日期 | 2014-04-02 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/17606]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Kou,Wang, Yuan-Yuan,Gao, Xiu,et al. Polycyclic Polyprenylated Acylphloroglucinols and Cytotoxic Constituents of Hypericum androsaemum[J]. CHEMISTRY & BIODIVERSITY,2012,9(6):1213-1220. |
| APA | Wang, Kou.,Wang, Yuan-Yuan.,Gao, Xiu.,Chen, Xuan-Qin.,Peng, Li-Yan.,...&Zhao, Qin-Shi.(2012).Polycyclic Polyprenylated Acylphloroglucinols and Cytotoxic Constituents of Hypericum androsaemum.CHEMISTRY & BIODIVERSITY,9(6),1213-1220. |
| MLA | Wang, Kou,et al."Polycyclic Polyprenylated Acylphloroglucinols and Cytotoxic Constituents of Hypericum androsaemum".CHEMISTRY & BIODIVERSITY 9.6(2012):1213-1220. |
入库方式： OAI收割
来源：昆明植物研究所
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