Asymmetric Synthesis of the Tricyclic Core of Calyciphylline A-Type Alkaloids via Intramolecular [3+2] Cycloaddition
文献类型：期刊论文
| 作者 | Wang, Lu1; Xu, Chen1; Chen, Li1; Hao, Xiaojiang2 ; Wang, David Zhigang1
|
| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2014-02-21 |
| 卷号 | 16期号:4页码:1076-1079 |
| 关键词 | BETA-HYDROXY KETONES NITRILE OXIDE CYCLOADDITION DAPHNIPHYLLUM ALKALOIDS TETRACYCLIC CORE DAPHNILACTONE-B RING-SYSTEM CONSTRUCTION REDUCTION DELTA-2-ISOXAZOLINES ROUTE |
| ISSN号 | 1523-7060 |
| 通讯作者 | Hao,XJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,Kunming 650204,Peoples R China. ; haoxj@mail.kib.ac.cn ; dzw@pkusz.edu.cn |
| 英文摘要 | Asymmetric synthesis of the [5-6-7] tricyclic system common to the Calyciphylline A-type alkaloids is reported, featuring Overman rearrangement, Heck cyclization, intramolecular [3 + 2] cycloaddition, diastereoselective hydrogenation, and Claisen rearrangement as strategic events. The approach is capable of installing the crucial carbonyl functionality as well as multiple stereogenic centers within a congested polycyclic ring skeleton. |
| 学科主题 | Chemistry, Organic |
| 类目[WOS] | Chemistry, Organic |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | BETA-HYDROXY KETONES ; NITRILE OXIDE CYCLOADDITION ; DAPHNIPHYLLUM ALKALOIDS ; TETRACYCLIC CORE ; DAPHNILACTONE-B ; RING-SYSTEM ; CONSTRUCTION ; REDUCTION ; DELTA-2-ISOXAZOLINES ; ROUTE |
| 收录类别 | SCI ; IC |
| 资助信息 | National Science Foundation of China [21290183, 21272014, 20972008, 20672160]; national "973 Project" of the State Ministry of Science and Technology [2012CB722602, 2010CB833200]; Shenzhen Bureau of Science and Technology |
| 语种 | 英语 |
| WOS记录号 | WOS:000331926800012 |
| 公开日期 | 2014-04-09 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/17942]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Peking Univ, Shenzhen Grad Sch, Sch Chem Biol & Biotechnol, Lab Chem Genom, Shenzhen 518055, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Lu,Xu, Chen,Chen, Li,et al. Asymmetric Synthesis of the Tricyclic Core of Calyciphylline A-Type Alkaloids via Intramolecular [3+2] Cycloaddition[J]. ORGANIC LETTERS,2014,16(4):1076-1079. |
| APA | Wang, Lu,Xu, Chen,Chen, Li,Hao, Xiaojiang,&Wang, David Zhigang.(2014).Asymmetric Synthesis of the Tricyclic Core of Calyciphylline A-Type Alkaloids via Intramolecular [3+2] Cycloaddition.ORGANIC LETTERS,16(4),1076-1079. |
| MLA | Wang, Lu,et al."Asymmetric Synthesis of the Tricyclic Core of Calyciphylline A-Type Alkaloids via Intramolecular [3+2] Cycloaddition".ORGANIC LETTERS 16.4(2014):1076-1079. |
入库方式： OAI收割
来源：昆明植物研究所
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