Surface functionalization of styrenic block copolymer elastomeric biomaterials with hyaluronic acid via a "grafting to" strategy
文献类型:期刊论文
作者 | Li XM ; Luan SF ; Yuan SS ; Song LJ ; Zhao J ; Ma J ; Shi HC ; Yang HW ; Jin J ; Yin JH |
刊名 | colloids and surfaces b-biointerfaces
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出版日期 | 2013 |
卷号 | 112页码:146-154 |
关键词 | POLYISOBUTYLENE-BASED BIOMATERIALS POLYETHYLENE-GLYCOL ACRYLATE POLY(STYRENE-B-(ETHYLENE-CO-BUTYLENE)-B-STYRENE) ELASTOMER COVALENT FUNCTIONALIZATION THERMOPLASTIC ELASTOMERS POLYMERIZATION HEPARIN PROTEIN IMMOBILIZATION POLYURETHANE |
ISSN号 | 0927-7765 |
通讯作者 | luan sf |
中文摘要 | as a biostable elastomer, the hydrophobicity of styrenic block copolymer (sbc) intensely limits its biomedical applications. in order to overcome such shortcoming, the sbc films were grafted with hyaluronic acid (ha) using a coupling agent. the surface chemistry of the modified films was examined by atr-ftir and xps techniques, and the surface morphology was visually described by afm. the biological performances of the ha-modified films were evaluated by a series of experiments, such as protein adsorption, platelet adhesion, and in vitro cytocompatibility. it was found that the ha-modified samples showed a low adhesiveness to fibroblast at the initial stage; however, it stimulated the growth of fibroblast. the l929 fibroblast growth presented a strong dependence on the molecular weight (mw) of ha. the samples modified with 17 kda ha exhibited the worst wettability and platelet adhesion, while providing the best results of supporting fibroblast proliferation. (c) 2013 elsevier b.v. all rights reserved. |
收录类别 | SCI收录期刊论文 |
语种 | 英语 |
WOS记录号 | WOS:000328593100022 |
公开日期 | 2014-04-15 |
源URL | [http://ir.ciac.jl.cn/handle/322003/49418] ![]() |
专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
推荐引用方式 GB/T 7714 | Li XM,Luan SF,Yuan SS,et al. Surface functionalization of styrenic block copolymer elastomeric biomaterials with hyaluronic acid via a "grafting to" strategy[J]. colloids and surfaces b-biointerfaces,2013,112:146-154. |
APA | Li XM.,Luan SF.,Yuan SS.,Song LJ.,Zhao J.,...&Yin JH.(2013).Surface functionalization of styrenic block copolymer elastomeric biomaterials with hyaluronic acid via a "grafting to" strategy.colloids and surfaces b-biointerfaces,112,146-154. |
MLA | Li XM,et al."Surface functionalization of styrenic block copolymer elastomeric biomaterials with hyaluronic acid via a "grafting to" strategy".colloids and surfaces b-biointerfaces 112(2013):146-154. |
入库方式: OAI收割
来源:长春应用化学研究所
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