Fluorescent Protein Capped Mesoporous Nanoparticles for Intracellular Drug Delivery and Imaging
文献类型：期刊论文
| 作者 | Yang XJ ; Li ZH ; Li M ; Ren JS ; Qu XG |
| 刊名 | chemistry-a european journal
 |
| 出版日期 | 2013 |
| 卷号 | 19期号:45页码:15378-15383 |
| 关键词 | RESPONSIVE CONTROLLED-RELEASE HISTIDINE-TAGGED PROTEINS SILICA NANOPARTICLES MAGNETIC NANOPARTICLES MECHANIZED NANOPARTICLES CARRIER SYSTEM ENZYME DNA NANOCONTAINERS MOLECULES |
| ISSN号 | 0947-6539 |
| 通讯作者 | ren js |
| 中文摘要 | a multifunctional system for intracellular drug delivery and simultaneous fluorescent imaging was constructed by using histidine-tagged, cyan fluorescent protein (cfp)-capped magnetic mesoporous silica nanoparticles (mmsns). this protein-capped multifunctional nanostructure is highly biocompatible and does not affect cell viability or proliferation. the cfp acts not only as a capping agent, but also as a fluorescent imaging agent. the nanoassembly was activated by histidine-based replacement, leading to release of drug molecules encapsulated in the nanopores into the bulk solution. the fluorescent imaging functionality would allow noninvasive tracking of the nanoparticles in the body. by combining the drug delivery with cell-imaging capability, these nanoparticles may provide valuable multifunctional nanoplatforms for biomedical applications. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000326290300039 |
| 公开日期 | 2014-04-15 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/49489]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Yang XJ,Li ZH,Li M,et al. Fluorescent Protein Capped Mesoporous Nanoparticles for Intracellular Drug Delivery and Imaging[J]. chemistry-a european journal,2013,19(45):15378-15383. |
| APA | Yang XJ,Li ZH,Li M,Ren JS,&Qu XG.(2013).Fluorescent Protein Capped Mesoporous Nanoparticles for Intracellular Drug Delivery and Imaging.chemistry-a european journal,19(45),15378-15383. |
| MLA | Yang XJ,et al."Fluorescent Protein Capped Mesoporous Nanoparticles for Intracellular Drug Delivery and Imaging".chemistry-a european journal 19.45(2013):15378-15383. |
入库方式： OAI收割
来源：长春应用化学研究所
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