Lighting up left-handed Z-DNA: photoluminescent carbon dots induce DNA B to Z transition and perform DNA logic operations
文献类型：期刊论文
| 作者 | Feng LY ; Zhao AD ; Ren JS ; Qu XG |
| 刊名 | nucleic acids research
 |
| 出版日期 | 2013 |
| 卷号 | 41期号:16页码:7987-7996 |
| 关键词 | CRYSTAL-STRUCTURE TRIPLEX DNA CONFORMATIONAL-CHANGES CIRCULAR-DICHROISM GENE-EXPRESSION QUANTUM DOTS BINDING NANOTUBES POLYMORPHISM DERIVATIVES |
| ISSN号 | 0305-1048 |
| 通讯作者 | qu xg |
| 中文摘要 | left-handed z-dna has been identified as a transient structure occurred during transcription. dna b-z transition has attracted much attention because of not only z-dna biological importance but also their relation to disease and dna nanotechnology. recently, photoluminescent carbon dots, especially highly luminescent nitrogen-doped carbon dots, have attracted much attention on their applications to bioimaging and gene/drug delivery because of carbon dots with low toxicity, highly stable photoluminescence and controllable surface function. however, it is still unknown whether carbon dots can influence dna conformation or structural transition, such as b-z transition. herein, based on our previous series work on dna interactions with carbon nanotubes, we report the first example that photoluminescent carbon dots can induce right-handed b-dna to left-handed z-dna under physiological salt conditions with sequence and conformation selectivity. further studies indicate that carbon dots would bind to dna major groove with gc preference. inspired by carbon dots lighting up z-dna and dna nanotechnology, several types of dna logic gates have been designed and constructed based on fluorescence resonance energy transfer between photoluminescent carbon dots and dna intercalators. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000325173300041 |
| 公开日期 | 2014-04-15 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/49645]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Feng LY,Zhao AD,Ren JS,et al. Lighting up left-handed Z-DNA: photoluminescent carbon dots induce DNA B to Z transition and perform DNA logic operations[J]. nucleic acids research,2013,41(16):7987-7996. |
| APA | Feng LY,Zhao AD,Ren JS,&Qu XG.(2013).Lighting up left-handed Z-DNA: photoluminescent carbon dots induce DNA B to Z transition and perform DNA logic operations.nucleic acids research,41(16),7987-7996. |
| MLA | Feng LY,et al."Lighting up left-handed Z-DNA: photoluminescent carbon dots induce DNA B to Z transition and perform DNA logic operations".nucleic acids research 41.16(2013):7987-7996. |
入库方式： OAI收割
来源：长春应用化学研究所
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