中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Highly Uniform alpha-NaYF4:Yb/Er Hollow Microspheres and Their Application as Drug Carrier

文献类型:期刊论文

作者Han YH ; Gai SL ; Ma PA ; Wang LZ ; Zhang ML ; Huang SH ; Yang PP
刊名inorganic chemistry
出版日期2013
卷号52期号:16页码:9184-9191
关键词DOPED NAYF4 NANOCRYSTALS EARTH FLUORIDE NANOCRYSTALS SUSTAINED-RELEASE PROPERTY UP-CONVERSION PHOSPHORS SHELL STRUCTURE CARBON SPHERES SILICA SPHERES NANOPARTICLES DELIVERY LUMINESCENCE
ISSN号0020-1669
通讯作者gai sl
中文摘要highly uniform alpha-nayf4:yb/er hollow microspheres have been successfully prepared via a simple two-step route. first, the core-shell structured mf@y(oh)co3:yb/er precursor was fabricated by a urea-based homogeneous precipitation method using colloidal melamine formaldehyde (mf) microspheres as template. then the y(oh)co3:yb/er precursor was transformed into hollow nayf4:yb/er (alpha and beta mixed phase) by a subsequent solvothermal method, and mf microspheres were dissolved in the solvent simultaneously. the mixed phase of nayf4:yb/er was transferred into pure alpha-nayf4:yb/er by calcination. the as-prepared hollow microspheres were well characterized by x-ray diffraction (xrd), scanning electron microscopy (sem), transmission electron microscopy (tem), energy-dispersive x-ray spectrum (eds), fourier transform infrared spectroscopy (ft-ir), thermogravimetric analysis (tga), and upconversion (uc) luminescence spectroscopy. it is found that the template can be removed without additional calcination or etching process. alpha-nayf4:yb/er hollow microspheres exhibit bright upconversion (uc) luminescence under 980 nm laser diode (ld) excitation. furthermore, the hollow microspheres show sustained and ph-dependent doxorubicin hydrochloride (d ox) release properties; in particular, the emission intensity increases with the release amount of drug, making the release process able to be tracked or monitored by the change of the emission intensity, which demonstrates the high potential of this kind of hollow fluorescent material in drug delivery fields.
收录类别SCI收录期刊论文
语种英语
WOS记录号WOS:000323460800006
公开日期2014-04-15
源URL[http://ir.ciac.jl.cn/handle/322003/49673]  
专题长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式
GB/T 7714
Han YH,Gai SL,Ma PA,et al. Highly Uniform alpha-NaYF4:Yb/Er Hollow Microspheres and Their Application as Drug Carrier[J]. inorganic chemistry,2013,52(16):9184-9191.
APA Han YH.,Gai SL.,Ma PA.,Wang LZ.,Zhang ML.,...&Yang PP.(2013).Highly Uniform alpha-NaYF4:Yb/Er Hollow Microspheres and Their Application as Drug Carrier.inorganic chemistry,52(16),9184-9191.
MLA Han YH,et al."Highly Uniform alpha-NaYF4:Yb/Er Hollow Microspheres and Their Application as Drug Carrier".inorganic chemistry 52.16(2013):9184-9191.

入库方式: OAI收割

来源:长春应用化学研究所

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