Self-assembled, functionalized graphene and DNA as a universal platform for colorimetric assays
文献类型：期刊论文
| 作者 | Tao Y ; Lin YH ; Ren JS ; Qu XG |
| 刊名 | biomaterials
 |
| 出版日期 | 2013 |
| 卷号 | 34期号:20页码:4810-4817 |
| 关键词 | RESONANCE ENERGY-TRANSFER PEROXIDASE-LIKE ACTIVITY GOLD NANOPARTICLES CARBON NANOTUBES SMALL MOLECULES REAL-TIME OXIDE FLUORESCENCE OLIGONUCLEOTIDE CORALYNE |
| ISSN号 | 0142-9612 |
| 通讯作者 | ren js |
| 中文摘要 | we have demonstrated a robust sensing strategy by employing single-stranded probe dna and the hemin-graphene hybrid (gh) to detect a broad range of targets including metal ions, dna and small molecules. this nearly "universal" biosensor approach is based on the dna-mediated assembly of the hemin-graphene composite upon addition of the targets. afterwards, gh aggregate resulting from dna hybridization will occur. the dna-gh hybrids will settle on the bottom of the vial after centrifugation, leaving behind a transparent supernatant. after incubation with tmb and h2o2, the colorimetric signal of the centrifugal supernatant will be significantly lower compared to that in the absence of targets. therefore, mediation of the assembly of dna on gh by targets can yield a facile means with tunable optical properties in response to concentration changes of the targets. this colorimetric "readout" offers great advantages such as the simple operation process, low-cost portable instrument and easy-to-use applications. therefore, we believe that this method promises a great potential of becoming a routine tool for quantitative detection of a wide spectrum of analytes for specific applications in biodiagnostics, nanoelectronics, and bionanotechnology. (c) 2013 elsevier ltd. all rights reserved. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000318464200012 |
| 公开日期 | 2014-04-15 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/49776]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Tao Y,Lin YH,Ren JS,et al. Self-assembled, functionalized graphene and DNA as a universal platform for colorimetric assays[J]. biomaterials,2013,34(20):4810-4817. |
| APA | Tao Y,Lin YH,Ren JS,&Qu XG.(2013).Self-assembled, functionalized graphene and DNA as a universal platform for colorimetric assays.biomaterials,34(20),4810-4817. |
| MLA | Tao Y,et al."Self-assembled, functionalized graphene and DNA as a universal platform for colorimetric assays".biomaterials 34.20(2013):4810-4817. |
入库方式： OAI收割
来源：长春应用化学研究所
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