Two-Dimensional Infrared (2DIR) Spectroscopy of the Peptide Beta3s Folding
文献类型：期刊论文
| 作者 | Lai ZZ ; Preketes NK ; Jiang J ; Mukamel S ; Wang J |
| 刊名 | journal of physical chemistry letters
 |
| 出版日期 | 2013 |
| 卷号 | 4期号:11页码:1913-1917 |
| 关键词 | DYNAMICS FORCE-FIELDS SECONDARY STRUCTURE MOLECULAR-DYNAMICS AMIDE-I PROTEIN SHEET HAIRPIN ENERGY SIMULATIONS CHARMM |
| ISSN号 | 1948-7185 |
| 通讯作者 | wang j |
| 中文摘要 | probing the underlying free-energy landscape, pathway, and mechanism is the key to understanding protein folding in theory and experiment. time-resolved two-dimensional infrared (2dir) with femtosecond laser pulses has emerged as a powerful tool for investigating the protein folding dynamics on much faster time scales than possible by nmr we have employed molecular dynamics simulations to compute 2dir spectra of the folding process of a peptide, beta3s. simulated nonchiral and chiral 2dir signals illustrate the variation of the spectra as the peptide conformation evolves along the free-energy landscape. chiral spectra show stronger changes than the nonchiral signals because cross peaks caused by the formation of the beta-sheet are clearly resolved. chirality-induced 2dir may be used to detect the folding of beta-sheet proteins with high spectral and temporal resolution. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000320214600026 |
| 公开日期 | 2014-04-15 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/49803]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Lai ZZ,Preketes NK,Jiang J,et al. Two-Dimensional Infrared (2DIR) Spectroscopy of the Peptide Beta3s Folding[J]. journal of physical chemistry letters,2013,4(11):1913-1917. |
| APA | Lai ZZ,Preketes NK,Jiang J,Mukamel S,&Wang J.(2013).Two-Dimensional Infrared (2DIR) Spectroscopy of the Peptide Beta3s Folding.journal of physical chemistry letters,4(11),1913-1917. |
| MLA | Lai ZZ,et al."Two-Dimensional Infrared (2DIR) Spectroscopy of the Peptide Beta3s Folding".journal of physical chemistry letters 4.11(2013):1913-1917. |
入库方式： OAI收割
来源：长春应用化学研究所
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