Plasma Proteins Adsorption Mechanism on Polyethylene-Grafted Poly(ethylene glycol) Surface by Quartz Crystal Microbalance with Dissipation
文献类型：期刊论文
| 作者 | Jin J ; Jiang W ; Yin JH ; Ji XL ; Stagnaro P |
| 刊名 | langmuir
 |
| 出版日期 | 2013 |
| 卷号 | 29期号:22页码:6624-6633 |
| 关键词 | SELF-ASSEMBLED MONOLAYERS CO-ACRYLIC ACID PLATELET-ADHESION BLOOD-COMPATIBILITY POLYMER SURFACES KINETICS BRUSHES OXIDE IMMOBILIZATION PHOSPHOLIPIDS |
| ISSN号 | 0743-7463 |
| 通讯作者 | jiang wc |
| 中文摘要 | protein adsorption has a vital role in biomaterial surface science because it is directly related to the hemocompatibility of blood-contacting materials. in this study, monomethoxy poly(ethylene glycol) (mpeg) with two different molecular weights was grafted on polyethylene as a model to elucidate the adsorption mechanisms of plasma protein through quartz crystal microbalance with dissipation (qcm-d). combined with data from platelet adhesion, whole blood clotting time, and hemolysis rate, the blood compatibility of pe-g-mpeg film was found to have significantly improved. two adsorption schemes were developed for real-time monitoring of protein adsorption. results showed that the preadsorbed bovine serum albumin (bsa) on the surfaces of pe-g-mpeg films could effectively inhibit subsequent adsorption of fibrinogen (fib). nonspecific protein adsorption of bsa was determined by surface coverage, not by the chain length of peg. dense peg brush could release more trapped water molecules to resist bsa adsorption. moreover, the preadsorbed fib could be gradually displaced by high-concentration bsa. however, the adsorption and displacement of fib was determined by surface hydrophilicity. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000320097000014 |
| 公开日期 | 2014-04-15 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/49808]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Jin J,Jiang W,Yin JH,et al. Plasma Proteins Adsorption Mechanism on Polyethylene-Grafted Poly(ethylene glycol) Surface by Quartz Crystal Microbalance with Dissipation[J]. langmuir,2013,29(22):6624-6633. |
| APA | Jin J,Jiang W,Yin JH,Ji XL,&Stagnaro P.(2013).Plasma Proteins Adsorption Mechanism on Polyethylene-Grafted Poly(ethylene glycol) Surface by Quartz Crystal Microbalance with Dissipation.langmuir,29(22),6624-6633. |
| MLA | Jin J,et al."Plasma Proteins Adsorption Mechanism on Polyethylene-Grafted Poly(ethylene glycol) Surface by Quartz Crystal Microbalance with Dissipation".langmuir 29.22(2013):6624-6633. |
入库方式： OAI收割
来源：长春应用化学研究所
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