Yolk-shell magnetic microspheres with mesoporous yttrium phosphate shells for selective capture and identification of phosphopeptides
文献类型：期刊论文
| 作者 | Cheng G ; Liu YL ; Wang ZG ; Li SM ; Zhang JL ; Ni JZ |
| 刊名 | journal of materials chemistry b
 |
| 出版日期 | 2013 |
| 卷号 | 1期号:30页码:3661-3669 |
| 关键词 | ARTIFICIAL RESTRICTION DNA DOUBLE-STRANDED DNA MASS-SPECTROMETRY PROTEIN-PHOSPHORYLATION AFFINITY PROBES HOLLOW SPHERES NANOPARTICLES ENRICHMENT DELIVERY CORE |
| ISSN号 | 2050-750x |
| 通讯作者 | zhang jl |
| 中文摘要 | architectural design is important to achieve appropriate chemical and biological properties of nanostructures. yolk-shell magnetic microspheres consisting of fe3o4 cores and porous and hollow ypo4 affinity shells have been designed and constructed. the yolk-shell magnetic microspheres have a saturation magnetization (m-s) value of 48.3 emu g(-1) with a negligible coercivity and remanence at 300 k and a bet specific surface area of 12.5 m(2) g(-1) with an average pore size of 10.1 nm for the mesoporous ypo4 shell. the novel multifunctional yolk-shell nanostructures can realize the selective capture, convenient magnetic separation and rapid identification of target phosphopeptides by taking advantage of the fe3o4 magnetic cores and the selective ypo4 affinity shells. sensitivity and selectivity of the affinity yolk-shell nanostructures were evaluated by digests of standard proteins and complex biosamples. 2678 unique phosphopeptides were captured and identified from the digest of mouse brain proteins. therefore, this work will be highly beneficial for future applications in the isolation and purification of biomolecules, in particular, low-abundance phosphopeptide biomarkers. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000321626200005 |
| 公开日期 | 2014-04-18 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/50252]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Cheng G,Liu YL,Wang ZG,et al. Yolk-shell magnetic microspheres with mesoporous yttrium phosphate shells for selective capture and identification of phosphopeptides[J]. journal of materials chemistry b,2013,1(30):3661-3669. |
| APA | Cheng G,Liu YL,Wang ZG,Li SM,Zhang JL,&Ni JZ.(2013).Yolk-shell magnetic microspheres with mesoporous yttrium phosphate shells for selective capture and identification of phosphopeptides.journal of materials chemistry b,1(30),3661-3669. |
| MLA | Cheng G,et al."Yolk-shell magnetic microspheres with mesoporous yttrium phosphate shells for selective capture and identification of phosphopeptides".journal of materials chemistry b 1.30(2013):3661-3669. |
入库方式： OAI收割
来源：长春应用化学研究所
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