Label-free electrochemical impedance genosensor based on 1-aminopyrene/graphene hybrids
文献类型：期刊论文
| 作者 | Luo LQ ; Zhang Z ; Ding YP ; Deng DM ; Zhu XL ; Wang ZX |
| 刊名 | nanoscale
 |
| 出版日期 | 2013 |
| 卷号 | 5期号:13页码:5833-5840 |
| 关键词 | WALLED CARBON NANOTUBES GRAPHENE-MODIFIED ELECTRODE DNA HYBRIDIZATION SENSORS RESONANCE ENERGY-TRANSFER FUNCTIONALIZED GRAPHENE SIGNAL AMPLIFICATION PAT GENE FILMS SHEETS OXIDE |
| ISSN号 | 2040-3364 |
| 通讯作者 | luo lq |
| 中文摘要 | in this work, we proposed a novel simple protocol for preparing 1-aminopyrene/graphene (apg) hybrids for fabricating label-free electrochemical impedance genosensor. graphene, with the structure of a single-atom-thick sheet of sp(2)-bonded carbon atoms, was anchored to 1-aminopyrene (1-ap) with the pyrenyl group via pi-stacking interaction. the morphology, conductivity, and interaction of apg hybrids were characterized by transmission electron microscopy (tem), cyclic voltammetry (cv), electrochemical impedance spectroscopy (eis), uv-visible (uv-vis) and fluorescence spectra. the amino-substituted oligonucleotide probe was conjugated to 1-ap by the cross-linker glutaraldehyde. the dna hybridization reaction of oligonucleotide probe with target dna was monitored by eis. under optimum conditions, the proposed biosensor exhibited high sensitivity and a low detection limit for detecting the complementary oligonucleotide. the target oligonucleotide could be quantified in a wide range of 1.0 x 10(-12) to 1.0 x 10(-8) m with good linearity (r = 0.9900) and low detection limit of 4.5 x 10(-13) m (s/n = 3). |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000320398300022 |
| 公开日期 | 2014-04-18 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/50255]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Luo LQ,Zhang Z,Ding YP,et al. Label-free electrochemical impedance genosensor based on 1-aminopyrene/graphene hybrids[J]. nanoscale,2013,5(13):5833-5840. |
| APA | Luo LQ,Zhang Z,Ding YP,Deng DM,Zhu XL,&Wang ZX.(2013).Label-free electrochemical impedance genosensor based on 1-aminopyrene/graphene hybrids.nanoscale,5(13),5833-5840. |
| MLA | Luo LQ,et al."Label-free electrochemical impedance genosensor based on 1-aminopyrene/graphene hybrids".nanoscale 5.13(2013):5833-5840. |
入库方式： OAI收割
来源：长春应用化学研究所
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