Polycations-functionalized water-soluble gold nanoclusters: a potential platform for simultaneous enhanced gene delivery and cell imaging
文献类型：期刊论文
| 作者 | Tao Y ; Li ZH ; Ju EG ; Ren JS ; Qu XG |
| 刊名 | nanoscale
 |
| 出版日期 | 2013 |
| 卷号 | 5期号:13页码:6154-6160 |
| 关键词 | TRANSGENIC MOUSE MODELS BIOLOGICAL APPLICATIONS DIRECTED SYNTHESIS NUCLEIC-ACIDS CANCER-CELLS NANOPARTICLES FLUORESCENT THERAPY DNA POLYMERS |
| ISSN号 | 2040-3364 |
| 通讯作者 | ren js |
| 中文摘要 | noble metal nanoclusters have emerged as a fascinating area of widespread interest in nanomaterials. herein, we report the synthesis of the pei-templated gold nanoclusters (pei-auncs) as an efficient carrier for gene delivery. the pei-auncs integrate the advantages of pei and auncs: the presence of auncs can effectively decrease the cytotoxicity of pei, making it possible to apply them in biological systems, while the cationic polymer layer pei with positive charges is essential for enhanced gene transfection efficiency. in addition, with excellent photoluminescent properties, the auncs also endow our system with the versatility of fluorescent imaging, indicating a great potential as an ideal fluorescent probe to track the transfection behavior. our studies provide strong evidence that the pei-auncs can be utilized as efficient gene delivery agents. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000320398300062 |
| 公开日期 | 2014-04-18 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/50257]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Tao Y,Li ZH,Ju EG,et al. Polycations-functionalized water-soluble gold nanoclusters: a potential platform for simultaneous enhanced gene delivery and cell imaging[J]. nanoscale,2013,5(13):6154-6160. |
| APA | Tao Y,Li ZH,Ju EG,Ren JS,&Qu XG.(2013).Polycations-functionalized water-soluble gold nanoclusters: a potential platform for simultaneous enhanced gene delivery and cell imaging.nanoscale,5(13),6154-6160. |
| MLA | Tao Y,et al."Polycations-functionalized water-soluble gold nanoclusters: a potential platform for simultaneous enhanced gene delivery and cell imaging".nanoscale 5.13(2013):6154-6160. |
入库方式： OAI收割
来源：长春应用化学研究所
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