Biocompatible Gd-III-functionalized fluorescent gold nanoclusters for optical and magnetic resonance imaging
文献类型：期刊论文
| 作者 | Sun GY ; Zhou L ; Liu YL ; Zhao ZB |
| 刊名 | new journal of chemistry
 |
| 出版日期 | 2013 |
| 卷号 | 37期号:4页码:1028-1035 |
| 关键词 | MRI CONTRAST AGENTS QUANTUM DOTS NANOPARTICLES SEMICONDUCTOR CYTOTOXICITY LUMINESCENCE STRATEGIES DYNAMICS CLUSTERS PROBES |
| ISSN号 | 1144-0546 |
| 通讯作者 | sun gy |
| 中文摘要 | fluorescent gold nanoclusters are ideal building blocks for the construction of multimodal imaging probes, but their use for optical and magnetic resonance imaging (mri) has remained unexplored. here we propose the use of bovine serum albumin stabilized gold nanoclusters as bimodal mri/optical nanoprobes by covalently grafting gd-dtpa onto the fluorescent gold nanoclusters. these nanoprobes show a higher relaxivity of 23.7 mm(-1) s(-1) per gd3+ relative to clinical gd-dtpa (4.3 mm(-1) s(-1)), while their fluorescence emission intensity is preserved. fluorescence imaging and t-1-weighted magnetic resonance imaging further reveal that these nanoprobes are highly suited for dual modality imaging application. this paves the way for investigating the gold nanocluster-based nanoprobes in a variety of imaging applications. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000316225300024 |
| 公开日期 | 2014-04-18 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/50342]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Sun GY,Zhou L,Liu YL,et al. Biocompatible Gd-III-functionalized fluorescent gold nanoclusters for optical and magnetic resonance imaging[J]. new journal of chemistry,2013,37(4):1028-1035. |
| APA | Sun GY,Zhou L,Liu YL,&Zhao ZB.(2013).Biocompatible Gd-III-functionalized fluorescent gold nanoclusters for optical and magnetic resonance imaging.new journal of chemistry,37(4),1028-1035. |
| MLA | Sun GY,et al."Biocompatible Gd-III-functionalized fluorescent gold nanoclusters for optical and magnetic resonance imaging".new journal of chemistry 37.4(2013):1028-1035. |
入库方式： OAI收割
来源：长春应用化学研究所
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